Generic Name: fulvestrant (ful VES trant)
Brand Name: Faslodex
What is fulvestrant?
Fulvestrant is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body.
Fulvestrant is used to treat a certain type of hormone-related breast cancer in postmenopausal women, when the cancer has spread to other parts of the body after treatment with anti-estrogen medication.
Fulvestrant is also used together with a medicine called palbociclib, to treat certain hormone-related breast cancer that has progressed or spread after treatment with hormonal therapy.
Fulvestrant may also be used for purposes not listed in this medication guide.
What is the most important information I should know about fulvestrant?
You should not receive fulvestrant if you are pregnant.
What should I discuss with my healthcare provider before I receive fulvestrant?
You should not receive this medicine if you are allergic to fulvestrant, or if you are pregnant.
To make sure fulvestrant is safe for you, tell your doctor if you have:
a bleeding or blood clotting disorder; or
thrombocytopenia (a low level of platelets in the blood).
Do not use fulvestrant if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 year after your treatment ends.
It is not known whether fulvestrant passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How is fulvestrant given?
Fulvestrant is given as two injections into a muscle of your buttock. Your doctor, nurse, or other healthcare provider will give you this injection.
Each injection must be given slowly, and can take up to 2 minutes to complete.
Fulvestrant is usually given once every 2 weeks at first, and then once a month. Do not miss any scheduled appointments.
When treatment also includes taking palbociclib capsules, you will most likely take your palbociclib dose once daily with food for 21 days in a row, followed by 7 days off the medicine. Follow your doctor's dosing instructions very carefully.
If you are a woman using fulvestrant together with palbociclib, tell your doctor if you are going through menopause (you have symptoms such as irregular menstrual periods, hot flashes, night sweats, or vaginal dryness). You may need to be treated with an additional hormone medication.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using fulvestrant.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your fulvestrant injection.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving fulvestrant?
This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Fulvestrant side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Common side effects may include:
bone pain, joint pain, muscle pain;
nausea, vomiting, loss of appetite, constipation;
weakness, feeling tired;
cough, trouble breathing;
abnormal liver function tests;
hot flashes; or
pain where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect fulvestrant?
Tell your doctor about all your current medicines and any you start or stop using, especially:
a blood thinner--warfarin, Coumadin, Jantoven.
This list is not complete. Other drugs may interact with fulvestrant, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Faslodex (fulvestrant)
Related treatment guides
Where can I get more information?
- Your doctor or pharmacist can provide more information about fulvestrant.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 7.02.
Date modified: October 14, 2016
Last reviewed: June 30, 2016