Generic Name: gemifloxacin (JEM i FLOX a sin)
Brand Name: Factive
Medically reviewed on December 21, 2017.
What is Factive?
Factive is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.
Factive is used to treat different types of bacterial infections in the lungs.
Fluoroquinolone antibiotics can cause serious or disabling side effects. Factive should be used only for infections that cannot be treated with a safer antibiotic.
Factive may also be used for purposes not listed in this medication guide.
Factive may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This effect may be more likely to occur if you are over 60, if you use steroid medication, or if you have had a kidney, heart, or lung transplant.
Call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.
Before taking this medicine
Factive may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking this medicine. Tendon problems may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant.
To make sure Factive is safe for you, tell your doctor if you have ever had:
tendon problems, arthritis or other joint problems;
slow heartbeats or other heart rhythm disorder (especially if you take medication to treat it);
long QT syndrome (in you or a family member);
trouble swallowing pills;
liver or kidney disease;
epilepsy or other seizure disorder;
a nerve disorder;
low levels of magnesium or potassium in your blood; or
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Factive passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Factive is not approved for use by anyone younger than 18 years old.
How should I take Factive?
Factive is usually taken once per day for 5 to 7 days. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take Factive with water, and drink extra fluids to keep your kidneys working properly while taking this medicine.
Factive may be taken with or without food, but take it at the same time each day.
Do not chew a Factive tablet. Swallow it whole.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Factive will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Factive?
Do not take Factive with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products as part of a regular meal, but do not use them alone when taking this medicine. They could make the medication less effective.
Factive may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Avoid exposure to sunlight or tanning beds. Factive can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.
Factive side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Factive may cause swelling or tearing of (rupture) a tendon. This medicine can also have serious effects on your nerves, and may cause permanent nerve damage. Stop using this medicine and call your doctor at once if you have:
signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions); or
nerve symptoms--numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position.
Stop using Factive and call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody;
fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
a seizure (convulsions);
increased pressure inside the skull--severe headaches, ringing in your ears, vision problems, pain behind your eyes; or
liver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Factive?
Some medicines can make Factive much less effective when taken at the same time. If you take any of the following medicines, take your this medicine dose 2 hours before or 3 hours after you take the other medicine:
vitamin or mineral supplements that contain aluminum, iron, magnesium, or zinc.
Tell your doctor about all your current medicines and any you start or stop using, especially:
a diuretic or "water pill";
heart rhythm medication;
medicine to treat depression or mental illness;
This list is not complete. Other drugs may interact with gemifloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 8.01.
More about Factive (gemifloxacin)
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- Drug class: quinolones