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Daunoxome

Generic Name: daunorubicin liposomal (DAW noe ROO bi sin LYE poe SOE mal)
Brand Name: Daunoxome

Medically reviewed on September 29, 2017

What is Daunoxome?

Daunoxome is a cancer (antineoplastic) medication. This medicine interferes with the growth of cancer cells and slows their growth and spread in the body.

Daunoxome is used to treat advanced HIV-associated Kaposi's sarcoma.

Daunoxome may also be used for purposes other than those listed in this medication guide.

Important Information

Daunoxome may cause dangerous effects on your heart. Call your doctor at once if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.

Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have back pain and chest tightness.

Daunoxome can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

Before taking this medicine

You should not use Daunoxome if you are allergic to it.

To make sure Daunoxome is safe for you, tell your doctor if you have:

Do not use Daunoxome if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Daunorubicin liposomal may pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

How is daunorubicin liposomal given?

Daunoxome is injected into a vein through an IV. A healthcare provider will give you this injection.

Before you receive each dose of Daunoxome, your heart function may need to be checked with an electrocardiograph or ECG (sometimes called an EKG). Your kidney and liver function may also need to be checked.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Daunoxome is injected.

Skin accidentally exposed to Daunoxome should be rinsed thoroughly with soap and warm water.

Daunoxome can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Daunoxome injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while using Daunoxome?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using Daunoxome, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Daunoxome side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have back pain and chest tightness.

Call your doctor at once if you have:

  • chest pain, shortness of breath (even with mild exertion), swelling, rapid weight gain;

  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum);

  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

  • pain, burning, irritation, or skin changes where the injection was given.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Daunoxome?

Other drugs may interact with daunorubicin liposomal, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

  • Your healthcare provider may have additional information about Daunoxome that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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