Generic Name: dorzolamide and timolol ophthalmic (dor ZOLE a mide and TYE moe lol off THAL mik)
Brand Name: Cosopt
What is dorzolamide and timolol ophthalmic?
Dorzolamide ophthalmic reduces the amount of fluid in the eye, which decreases pressure inside the eye.
Timolol ophthalmic is a beta-blocker that also reduces pressure inside the eye.
Dorzolamide and timolol ophthalmic (for the eyes) is a combination medicine used to treat certain types of glaucoma and other causes of high pressure inside the eye.
Dorzolamide and timolol ophthalmic may also be used for purposes not listed in this medication guide.
What is the most important information I should know about dorzolamide and timolol ophthalmic?
You should not use this medication if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or a serious heart condition such as "AV block," slow heartbeats, heart failure, or if you have recently had a heart attack.
What should I discuss with my healthcare provider before using dorzolamide and timolol ophthalmic?
You should not use this medication if you are allergic to dorzolamide (Cosopt or Trusopt) or timolol (Blocadren, Betimol, Istalol, Timoptic), or if you have:
a history of asthma;
chronic obstructive pulmonary disease (COPD); or
a serious heart condition such as "AV block," slow heartbeats, heart failure, or if you have recently had a heart attack.
To make sure dorzolamide and timolol ophthalmic is safe for you, tell your doctor if you have:
breathing problems such as bronchitis or emphysema;
a history of heart disease or congestive heart failure;
a muscle disorder such as myasthenia gravis;
liver disease; or
a thyroid disorder.
FDA pregnancy category C. It is not known whether dorzolamide and timolol ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether dorzolamide and timolol ophthalmic passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine.
Do not use this medicine in a child younger than 2 years old.
How should I use dorzolamide and timolol ophthalmic?
Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using the eye drops before putting your contact lenses in.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Wash your hands before using the eye drops.
To apply the eye drops:
Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
Wait at least 10 minutes before using any other eye drops your doctor has prescribed.
Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.
Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
Tell your doctor right away if you have any eye injury or infection, or if you need to have any type of surgery, especially eye surgery. You may need to stop using dorzolamide and timolol ophthalmic for a short time.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include feeling short of breath, confusion, muscle pain or weakness, fast or slow heart rate, wheezing, trouble breathing, chest pain, fainting, or seizure (convulsions).
What should I avoid while using dorzolamide and timolol ophthalmic?
Dorzolamide and timolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.
Do not use other eye medications during treatment with dorzolamide and timolol ophthalmic unless your doctor tells you to.
Dorzolamide and timolol ophthalmic side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Although the risk of serious side effects is low when dorzolamide and timolol is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.
Stop using the medicine and call your doctor at once if you have:
swelling or redness of your eyelids;
eye redness, pain, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
wheezing, gasping, or other breathing problems;
swelling, rapid weight gain;
feeling short of breath, even with mild exertion; or
severe skin reaction: fever, sore throat, cough, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
bitter or unusual taste in your mouth;
blurred vision; or
burning, stinging, or itching in your eyes.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect dorzolamide and timolol ophthalmic?
Other drugs may interact with dorzolamide and timolol ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about Cosopt (dorzolamide / timolol ophthalmic)
- Cosopt drops
- Cosopt (Advanced Reading)
- Cosopt Ocumeter (Advanced Reading)
- Cosopt Ocumeter Plus (Advanced Reading)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about dorzolamide and timolol ophthalmic.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 6.03.
Date modified: January 10, 2017
Last reviewed: September 10, 2013