Generic Name: ciprofloxacin (oral) (SIP roe FLOX a sin)
Brand Name: Cipro, Cipro XR, Proquin XR
Medically reviewed on Aug 15, 2018
What is Cipro XR?
Cipro XR is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. This medicine is used to treat different types of bacterial infections. This medicine is also used to treat people who have been exposed to anthrax or certain types of plague.
Fluoroquinolone antibiotics can cause serious or disabling side effects that may not be reversible. Cipro XR should be used only for infections that cannot be treated with a safer antibiotic.
Cipro XR may also be used for purposes not listed in this medication guide.
Cipro XR can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or low blood sugar.
Stop taking Cipro XR and call your doctor at once if you have symptoms such as: headache, hunger, irritability, feeling anxious or shaky, numbness, tingling, burning pain, confusion, agitation, paranoia, problems with memory or concentration, or thoughts of suicide.
Cipro XR may cause swelling or tearing of a tendon. Stop taking this medicine and call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints.
Before taking this medicine
You should not use Cipro XR if you are allergic to it, or if:
you also take tizanidine; or
Cipro XR may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking this medicine. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).
Tell your doctor if you have ever had:
tendon problems, bone problems, arthritis, or other joint problems (especially in children);
a muscle or nerve disorder, such as myasthenia gravis;
long QT syndrome (in you or a family member); or
heart problems, or low levels of potassium in your blood (hypokalemia).
Do not give this medicine to a child without medical advice.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
You should not breast-feed while using this medicine.
How should I take Cipro XR?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take Cipro XR with or without food, at the same time each day.
Shake the oral suspension (liquid) for 15 seconds before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Do not give Cipro XR suspension through a feeding tube.
Swallow the extended-release tablet whole and do not crush, chew, or break it.
Use Cipro XR for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Cipro XR will not treat a viral infection such as the flu or a common cold.
Do not share Cipro XR with another person.
Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze. Throw away any unused liquid after 14 days.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Cipro XR?
Do not take Cipro XR with dairy products such as milk or yogurt, or with calcium- fortified juice. You may eat or drink these products with your meals, but do not use them alone when taking this medicine. They could make the medication less effective.
Using caffeine while taking Cipro XR can increase the effects of the caffeine.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
Cipro XR could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Tell your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.
Avoid driving or hazardous activity until you know how Cipro XR will affect you. Your reactions could be impaired.
Cipro XR side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Cipro XR can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).
Stop taking this medicine and call your doctor at once if you have:
nerve symptoms in your hands, arms, legs, or feet--numbness, weakness, tingling, burning pain;
serious mood or behavior changes--nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; or
signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).
Also, stop using Cipro XR and call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody;
fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
the first sign of any skin rash, no matter how mild;
muscle weakness, breathing problems;
little or no urination;
jaundice (yellowing of the skin or eyes); or
increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.
Common side effects may include:
nausea, vomiting, diarrhea, stomach pain;
vaginal itching or discharge;
abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Cipro XR?
Some medicines can make Cipro XR much less effective when taken at the same time. If you take any of the following medicines, take your this medicine dose 2 hours before or 6 hours after you take the other medicine.
vitamin or mineral supplements that contain calcium, iron, magnesium, or zinc.
Tell your doctor about all your other medicines, especially:
a diuretic or "water pill";
heart rhythm medication;
insulin or oral diabetes medicine (check your blood sugar regularly);
medicine to treat depression or mental illness;
steroid medicine (such as prednisone); or
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 21.01.
More about Cipro XR (ciprofloxacin)
- Cipro XR Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: quinolones
Other brands: Proquin XR