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Brompheniramine, chlophedianol, and pseudoephedrine

Generic name: brompheniramine, chlophedianol, and pseudoephedrine (BROM fen IR a meen, KLOE fe DYE a nol, and SOO doe ee FED rin)
Brand name: Atuss DA, Dicel CD, Y-Tuss
Drug class: Upper respiratory combinations

What is brompheniramine, chlophedianol, and pseudoephedrine?

Brompheniramine is an antihistamine. Chlophedianol is a cough suppressant. Pseudoephedrine is a decongestant.

Brompheniramine, chlophedianol, and pseudoephedrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including cough, sneezing, runny or stuffy nose, and itchy, watery eyes.

brompheniramine, chlophedianol, and pseudoephedrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Brompheniramine, chlophedianol, and pseudoephedrine may also be used for purposes not listed in this medication guide.


Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use this medicine only to make a child sleepy.

Before taking this medicine

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use this medicine if you are allergic to brompheniramine, chlophedianol, or pseudoephedrine.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

How should I take brompheniramine, chlophedianol, and pseudoephedrine?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?

Since brompheniramine, chlophedianol, and pseudoephedrine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking brompheniramine, chlophedianol, and pseudoephedrine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

Drinking alcohol with this medicine can cause side effects.

brompheniramine, chlophedianol, and pseudoephedrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe drowsiness, dizziness, or nervousness;

  • trouble sleeping; or

  • little or no urination.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

  • drowsiness;

  • constipation;

  • dry mouth, nose, or throat;

  • blurred vision; or

  • feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

Brompheniramine, chlophedianol, and pseudoephedrine dosing information

Usual Adult Dose for Nasal Congestion:

Brompheniramine/chlophedianol/PSE 2 mg-12.5 mg-30 mg/5 mL oral liquid:
10 mLs orally every 6 to 8 hours not to exceed 4 doses/daily.

Usual Pediatric Dose for Nasal Congestion:

Brompheniramine/chlophedianol/PSE 2 mg-12.5 mg-30 mg/5 mL oral liquid:
6 to 11 years: 5 mLs orally every 6 to 8 hours not to exceed 4 doses/daily.
12 years or older: 10 mLs orally every 6 to 8 hours not to exceed 4 doses/daily.

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What other drugs will affect brompheniramine, chlophedianol, and pseudoephedrine?

Ask a doctor or pharmacist before using brompheniramine, chlophedianol, and pseudoephedrine with any other medicines, especially drugs that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.