Generic Name: bisoprolol (BIS oh PROE lol)
Brand Name: Zebeta
What is bisoprolol?
Bisoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).
Bisoprolol is used to treat hypertension (high blood pressure).
Bisoprolol may also be used for purposes not listed in this medication guide.
What is the most important information I should know about bisoprolol?
You should not use bisoprolol if you have a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.
What should I discuss with my healthcare provider before taking bisoprolol?
You should not use bisoprolol if you you are allergic to it, or if you have a serious heart condition such as:
severe heart failure; or
slow heartbeats that have caused you to faint.
To make sure bisoprolol is safe for you, tell your doctor if you have:
congestive heart failure or other heart problems;
coronary artery disease (hardened arteries);
circulation problems (such as Raynaud's syndrome);
asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
diabetes (taking bisoprolol can make it harder for you to tell when you have low blood sugar);
liver or kidney disease;
a thyroid disorder; or
a history of allergies.
It is not known whether bisoprolol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether bisoprolol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Bisoprolol is not approved for use by anyone younger than 18 years old.
How should I take bisoprolol?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Do not skip doses or stop taking bisoprolol without first talking to your doctor. Stopping suddenly may make your condition worse or cause other serious heart problems.
If you need surgery, tell the surgeon ahead of time that you are using bisoprolol.
Your blood pressure will need to be checked often.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking bisoprolol?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. It can increase some of the side effects of bisoprolol.
Bisoprolol side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
shortness of breath (even with mild exertion), swelling, rapid weight gain;
slow heart rate;
pounding heartbeats or fluttering in your chest;
numbness, tingling, or cold feeling in your hands or feet;
a light-headed feeling, like you might pass out;
eye pain, vision problems; or
bronchospasm (wheezing, chest tightness, trouble breathing).
Common side effects may include:
sleep problems (insomnia);
cold symptoms such as stuffy nose, runny nose, cough, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Bisoprolol dosing information
Usual Adult Dose for Hypertension:
Initial dose: 5 mg orally once a day
Dose Titration: If desired response is not achieved, may increase the dose to 10 mg, then 20 mg if necessary
Maximum dose: 20 mg per day
-Dosage should be individualized to the patient; some patients may benefit from a starting dose of 2.5 mg once a day.
-In clinical trials, blood pressure lowering effects were seen at 1 week and changed little thereafter.
Use: Management of hypertension, alone or with other antihypertensive agents
What other drugs will affect bisoprolol?
Tell your doctor about all your current medicines and any you start or stop using, especially:
insulin or oral diabetes medicine;
heart or blood pressure medicine--clonidine, digitalis, digoxin, diltiazem, reserpine, or verapamil.
This list is not complete. Other drugs may interact with bisoprolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about bisoprolol
- Other brands: Zebeta
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about bisoprolol.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 9.01.
Date modified: January 10, 2017
Last reviewed: August 23, 2016