Generic Name: sulfanilamide vaginal (SUL fa NIL a mide)
Brand Name: AVC
Medically reviewed on Jan 8, 2018
What is AVC?
Sulfanilamide is an antibiotic that fights bacteria.
AVC is used to treat vaginal yeast infections.
AVC may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use AVC if you are allergic to it, or if you have:
stomach pain; or
foul-smelling vaginal discharge.
To make sure AVC is safe for you, tell your doctor if you have:
an allergy to sulfa drugs.
It is not known whether AVC will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to use an applicator for vaginal medicine if you are more than 7 months pregnant.
Sulfanilamide vaginal can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
AVC is not approved for use by anyone younger than 18 years old.
How should I use AVC?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Do not take by mouth. AVC is for use only in the vagina.
AVC is usually applied twice per day for 30 days. Follow your doctor's dosing instructions.
Wash your hands before and after inserting this medication.
Insert sulfanilamide cream into the vagina using the applicator provided with this medicine.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
Call your doctor if your symptoms do not improve after a few days of treatment, or if you have new or worsening symptoms.
You may continue using AVC during your menstrual period.
Use a sanitary napkin to prevent this medicine from staining your underwear. Do not use a tampon.
Store at room temperature away from moisture, heat, and cold. Keep the tube tightly closed when not in use.
Do not share this medicine with another person, even if they have the same symptoms you have.
What happens if I miss a dose?
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
An overdose of AVC is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
What should I avoid while using sulfanilamide vaginal?
Do not use other vaginal medications unless your doctor tells you to. Avoid using vaginal cleansers or douche products while you are treating a vaginal infection.
Avoid wearing tight-fitting, synthetic clothing such as Spandex or nylon that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection clears up.
Avoid sexual intercourse or use a condom to prevent spreading the infection to your sexual partner.
AVC side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using AVC and call your doctor at once if you have severe or worsening vaginal symptoms, such as itching and burning.
Although the risk of serious side effects is low when sulfanilamide is used in the vagina, side effects can occur if the medicine is absorbed into your bloodstream. Call your doctor at once if you have:
sudden weakness or ill feeling;
fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing;
headache, hunger, weakness, confusion, irritability; or
Common side effects may include:
mild burning after inserting the medicine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect AVC?
It is not likely that other drugs you take orally or inject will have an effect on sulfanilamide used in the vagina. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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