Skip to main content

How long does it take for Soliqua to work?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Sep 9, 2024.

Official answer

by Drugs.com

Soliqua 100/33 is a combination of insulin glargine, a long-acting insulin, and lixisenatide, a GLP-1 receptor agonist. Soliqua starts to lower levels of glucose (sugar) in the blood two hours after injection and keeps working evenly for 20 to 24 hours in most patients. Soliqua helps to control blood sugar in patients with type 2 diabetes throughout the day and night.

Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Lixisenatide is a diabetes medicine that helps your pancreas produce insulin more efficiently.

Soliqua 100/33 is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. Soliqua 100/33 is not for treating type 1 diabetes.

When should I take Soliqua?

Soliqua is injected subcutaneously (under the skin) once a day, at the same time every day, within 1 hour of your first meal each day. Your doctor, nurse or pharmacist can teach you how to inject this medicine by yourself.

Your starting dose of Soliqua depends upon the amount and type of medications you took before starting this treatment. Your doctor will slowly titrate (change) your Soliqua dose based on how the medicine affects your blood sugar.

Related questions

Bottom Line

  • Soliqua starts to lower levels of glucose (sugar) in the blood two hours after injection and keeps working evenly for 20 to 24 hours in most patients.
  • Soliqua helps to control blood sugar in patients with type 2 diabetes throughout the day and night.
  • Soliqua is injected subcutaneously (under the skin) once a day, at the same time every day, within 1 hour of your first meal each day.

This is not all the information you need to know about Soliqua 100/33 for safe and effective use. Review the full Soliqua 100/33 information here, and discuss this information with your doctor or other health care provider.

References
  • Soliqua 100/33 [product information]. Nov. 2019. Sanofi-Aventis U.S. LLC Bridgewater, NJ. Accessed September 17, 2020 at http://products.sanofi.us/soliqua100-33/Soliqua100-33.pdf
  • Soliqua (online). August 2019. Sanofi-Aventis U.S. LLC Accessed September 17, 2020 at https://www.soliqua100-33.com/how-to-use

Read next

Does Soliqua come with pen needles?

No, the pen needles are not included in your box of Soliqua, you will need to buy them separately. If you are not sure which needles to use, ask your doctor or pharmacist before you buy them. You should only use needles that are compatible with your Soliqua 100/33 prefilled pen. Continue reading

Does Soliqua cause weight gain?

Weight gain is not a common side effect for Soliqua (insulin glargine/lixisenatide). In some clinical studies, patients using Soliqua had an average weight loss of 0.1 and 0.3 kg (0.2 and 0.7 lb). Continue reading

How many units are in a Soliqua pen?

The Soliqua 100/33 pen injector contains 100 units of insulin glargine per one milliliter (mL). It also contains 33 mcg of lixisenatide per mL. Each Soliqua pen holds a total of 3 mL, so there is a total of 300 units of insulin glargine per pen. The maximum dose of Soliqua 100/33 is 60 units daily. Continue reading

Related medical questions

Drug information

Related support groups