How long does it take for Promacta (eltrombopag olamine) to work?
Medically reviewed by N. France, BPharm. Last updated on Nov 24, 2020.

Official Answer
by Drugs.comPromacta (Revolade, eltrombopag olamine) is a thrombopoietin receptor agonist that is used to increase low blood platelet counts (thrombocytopenia) in certain people with chronic immune thrombocytopenia (ITP) and severe aplastic anemia. Platelets are blood cells that help to form clots and stop bleeding.
How quickly does Promacta work in ITP and severe aplastic anemia?
Uses | Time to work |
Thrombocytopenia To treat thrombocytopenia in people with ITP who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. |
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Thrombocytopenia with hepatitis C To treat thrombocytopenia in patients with chronic hepatitis C to allow the initiation and maintenance of interferon-based therapy. |
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Aplastic anemia combination therapy In combination with standard immunosuppressive therapy for the first-line treatment of severe aplastic anemia. |
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Severe aplastic anemia To treat patients with severe aplastic anemia who have had insufficient response to immunosuppressive therapy. |
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References
- Food and Drug Administration (FDA). Promacta. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125554s071lbl.pdf. [Accessed November 25, 2020].
- Townsley DM, Scheinberg P, Winkler T, et al. Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia. N Engl J Med. 2017;376(16):1540-1550. doi:10.1056/NEJMoa1613878.
- Olnes MJ, Scheinberg P, Calvo KR, et al. Eltrombopag and improved hematopoiesis in refractory aplastic anemia [published correction appears in N Engl J Med. 2012 Jul 19;367(3):284]. N Engl J Med. 2012;367(1):11-19. doi:10.1056/NEJMoa1200931.
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