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What condition is Crysvita (burosumab-twza) used to treat?

Medically reviewed by Last updated on Oct 1, 2019.

Official Answer


Crysvita is used to treat a rare inherited form of rickets known as X-linked hypophosphatemia (XLH).

X-linked hypophosphatemia (XLH) leads to low phosphorus levels in the body and treatment with vitamin D is not effective for this type of rickets. Impaired bone growth in childhood and problems with bone mineralization can occur.

Crysvita (burosumab-twza) is classified as a fibroblast growth factor 23 (FGF23) blocking antibody. It is used to treat X-linked hypophosphatemia in adult and pediatric patients 6 months of age and older.

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