Medically reviewed on February 1, 2018
A bone scan is a nuclear imaging test that helps diagnose and track several types of bone disease. Your doctor may order a bone scan if you have unexplained skeletal pain, bone infection or a bone injury that can't be seen on a standard X-ray.
A bone scan is also an important tool for detecting cancer that has spread (metastasized) to the bone from the tumor's original location, such as the breast or prostate.
Why it's done
If you have unexplained bone pain, a bone scan might help determine the cause. The test is very sensitive to variation in bone metabolism. The ability to scan the entire skeleton makes a bone scan very helpful in diagnosing a wide range of bone disorders, including:
- Paget's disease of bone
- Cancer originating in bone
- Cancer that has metastasized to bone from a different site
- Infection of the joints, joint replacements or bones (osteomyelitis)
- Fibrous dysplasia
- Impaired blood supply to bones or death of bone tissue (avascular necrosis)
Scan A shows hot spots (dark areas) in both knees, a sign of arthritis, and a possible fracture in the second toe of the right foot. Otherwise it shows normal bone metabolism. Scan B shows numerous bone hot spots, a result of cancer that has spread to multiple locations.
A bone scan poses no greater risk than do conventional X-ray procedures. The tracers used in a bone scan produce very little radiation exposure — less than half that of a CT scan.
How you prepare
You don't need to restrict your diet or avoid particular activities in preparation for a bone scan. Immediately before the test, though, you may be asked to remove jewelry or other metal objects.
Bone scans aren't usually performed on pregnant women or nursing mothers because of concerns about radiation exposure to the baby. Tell your doctor if you're pregnant — or think you might be pregnant — or if you're nursing.
What you can expect
A bone scan is a nuclear imaging procedure. In nuclear imaging, tiny amounts of radioactive materials (tracers) are injected into a vein and taken up in varying amounts at different sites in the body.
Areas of the body where cells and tissues are repairing themselves most actively take up the largest amounts of tracer. Nuclear images highlight these areas, suggesting the presence of abnormalities associated with disease or injury.
A bone scan includes both an injection and the actual scan.
Tracers will be injected into a vein in your arm. The amount of time between the injection and scan varies, depending on the reason your doctor has ordered the scan.
Some images may be taken immediately after the injection. You will need to wait for two to four hours, however, before the main images are taken, to allow the tracer to circulate and be absorbed by your bones. Your doctor may recommend that you drink several glasses of water while you wait.
You'll be asked to lie still on a table while an armlike device supporting a tracer-sensitive camera passes back and forth over your body. The procedure is painless.
A scan of your entire skeleton usually takes less than 30 minutes. Scanning a limited area of your body takes less time.
Your doctor might order a three-phase bone scan, which includes a series of images taken at different times. A number of images are taken as the tracer is injected, then shortly after the injection, and again two to four hours later.
To better see some bones in your body, your doctor might order additional imaging called single-photon emission computerized tomography (SPECT). This imaging can help analyze conditions that are especially deep in your bone or in places that are difficult to see.
For a SPECT scan, the camera rotates around your body, taking images as it rotates. The additional SPECT images take about 35 minutes.
After the test
A bone scan generally has no side effects, and no follow-up care is needed. The radioactivity in the tracers is mostly removed from your body after one day and completely eliminated by two days.
A doctor who specializes in reading images (radiologist) will look for evidence of abnormal bone metabolism on the scans. These areas appear as darker "hot spots" and lighter "cold spots" where the tracers have or haven't accumulated.
Although a bone scan is very sensitive to abnormalities in bone metabolism, it's less helpful in determining the exact cause of the abnormality. If you have a bone scan that shows hot spots, more testing may be needed to determine the cause.