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Sclerosing mesenteritis

Medically reviewed by Last updated on Nov 15, 2023.


Sclerosing mesenteritis is a condition in which tissue that holds the small intestines in place, called the mesentery, becomes inflamed and forms scar tissue. The condition also is called mesenteric panniculitis. Sclerosing mesenteritis is rare, and it's not clear what causes it.

Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment.

In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery.


The mesentery is a fold of membrane that attaches the intestine to the abdominal wall and holds it in place.


Symptoms of sclerosing mesenteritis include pain in the belly, vomiting, bloating, diarrhea and fever. Sometimes people don't have any symptoms.


The cause of sclerosing mesenteritis is not known.


Tests and procedures used to diagnose sclerosing mesenteritis include:


You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition.

If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment.


Medicines for sclerosing mesenteritis are used to control inflammation. Medicines may include:


You may need surgery if the scar tissue blocks food from moving through your digestive tract.

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