Label Changes for:
OxyContin (oxycodone hydrochloride) controlled-release tablets
Changes have been made to the PRECAUTIONS sections of the safety label.
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) -- September 2009
(included adding the 60-mg strength to opioid tolerance language throughout the label; i.e. Boxed Warning, Warning)
- Oxycodone is metabolized in part by cytochrome P450 2D6 and cytochrome P450 3A4 and in theory can be affected by other drugs.