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In the US, Topotecan (topotecan systemic) is a member of the drug class miscellaneous antineoplastics and is used to treat Cancer, Cervical Cancer, Ovarian Cancer and Small Cell Lung Cancer.

US matches:

UK matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Cytostatic agent

Topoisomerase I inhibitor

Chemical Name

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimetylamino)metyl]-4-etyl-4,9-dihydroxy-

Foreign Names

  • Topotecanum (Latin)
  • Topotecan (German)
  • Topotecane (French)
  • Topotecan (Spanish)

Generic Names

  • Topotecan (OS: BAN)
  • Topotecan Hydrochloride (OS: BANM, USAN)
  • E 89/001 (IS)
  • NSC 609699 (IS)
  • SKF S-104864-A (IS: SmithKlineBeec)

Brand Names

  • Asotecan
    Raffo, Argentina
  • Cantop
    Dr. Reddy's, India
  • Hycamtin
    GlaxoSmithKline, Ireland; GlaxoSmithKline, Serbia; Novartis Europharm, Slovenia
  • Potactasol
    Actavis, Lithuania; Actavis, Romania; Actavis Group, Poland
  • Topofar
    Fidifarm, Croatia (Hrvatska)
  • Topotecan Accord
    Accord, Lithuania; Accord Healthcare Limited, Slovakia
  • Topotecan Actavis
    Actavis, Bosnia & Herzegowina; Actavis, Lithuania; Actavis Group, Greece; Actavis Group, Poland; Actavis Italy, Italy
  • Topotecan AHCL
    Accord Healthcare, Italy
  • Topotecan Alpha-Medical
    Alpha-Medical, Croatia (Hrvatska)
  • Topotecan Cipla
    Cipla, Poland
  • Topotecan Eagle
    Eagle Laboratories, Lithuania
  • Topotecan Ebewe
    Ebewe, Lithuania; Ebewe, Poland
  • Topotecan Fresenius
    Fresenius, Malta
  • Topotecan Fresenius Kabi
    Fresenius Kabi Oncology, Greece
  • Topotecan Hospira
    Hospira, Bosnia & Herzegowina; Hospira, Greece; Hospira, Lithuania; Hospira, Poland; Hospira, Slovakia; Hospira Italia, Italy
  • Topotecan Kabi
    Alvogen, Croatia (Hrvatska); Fresenius Kabi, Croatia (Hrvatska); Fresenius Kabi, Italy; Fresenius Kabi, Poland; Fresenius Kabi Oncology, Lithuania
  • Topotecan Logenex
    Logenex Pharm, Poland
  • Topotecan medac
    medac, Poland; medac, Slovakia
  • Topotecan Microsules
    Microsules Arg, Argentina
  • Topotecan Mylan
    Mylan, Poland
  • Topotecan Strides
    Strides Arcolab, Poland
  • Topotecan Teva
    Teva, Greece; Teva, Hungary; Teva Italia, Italy
  • Topotecan Varifarma
    Varifarma, Argentina
  • Topotecan Vitalchem
    Vitalchem, Colombia
  • Topotecanum Accord
    Accord Healthcare, Poland
  • Ai Tuo
    Hengrui, China
  • Aoluona
    AosaiKang Pharmaceutical, China
  • Bo En
    Yangtze River Pharma, China
  • Hycamtin
    GlaxoSmithKline, Australia; GlaxoSmithKline, Brazil; GlaxoSmithKline, Canada; GlaxoSmithKline, Chile; GlaxoSmithKline, China; GlaxoSmithKline, Germany; GlaxoSmithKline, Denmark; GlaxoSmithKline, Spain; GlaxoSmithKline, Finland; GlaxoSmithKline, Greece; GlaxoSmithKline, Hong Kong; GlaxoSmithKline, Croatia (Hrvatska); GlaxoSmithKline, Ireland; GlaxoSmithKline, Israel; GlaxoSmithKline, Italy; GlaxoSmithKline, Lithuania; GlaxoSmithKline, Malaysia; GlaxoSmithKline, Netherlands; GlaxoSmithKline, Norway; GlaxoSmithKline, Oman; GlaxoSmithKline, Philippines; GlaxoSmithKline, Sweden; GlaxoSmithKline, Singapore; GlaxoSmithKline, Slovakia; GlaxoSmithKline, Thailand; GlaxoSmithKline, Taiwan; GlaxoSmithKline, United States; GlaxoSmithKline, Vietnam; GlaxoSmithKline, South Africa; GlaxoSmithKline UK, United Kingdom; GSK, Belgium; GSK, Turkey; Nippon Kayaku, Japan; Novartis, France; Novartis Pharma, Switzerland; Smith Kline & French, Portugal; SmithKline Beecham, Austria; SmithKline Beecham, Czech Republic; SmithKline Beecham, Hungary; SmithKline Beecham, Iceland; SmithKline Beecham, Poland; SmithKline Beecham, Romania; Wellcome Limited, Bosnia & Herzegowina
  • Jin Xi Su
    Zhongxing Hanfang Pharmaceutical, China
  • Oncotecan
    Medicamenta Ecuatoriana, Ecuador
  • Potactasol
    Actavis, France; Actavis, Hungary; Actavis, Israel; Actavis, Latvia; Actavis, Netherlands; Actavis, Norway; Actavis, Portugal; Actavis, Sweden; Actavis UK, United Kingdom
  • Sheng Cheng
    Haibin, China
  • Tisogen
    Bioprofarma, Argentina
  • Topocan
    Ariti, Greece; Korea United Pharm, Georgia
  • Topokebir
    Aspen, Argentina
  • Topotecan Accord
    Accord, Denmark; Accord, Spain; Accord, Netherlands; Accord Healthcare, Austria; Accord Healthcare, Bulgaria; Accord Healthcare, Estonia; Accord Healthcare, United Kingdom; Accord Healthcare, Georgia; Accord Healthcare, Malta; Accord Healthcare, Norway; Accord Healthcare, Romania; Accord Healthcare, Sweden; Bendalis, Germany
  • Topotecan Accord Healthcare
    Accord Healthcare, Belgium
  • Topotecan Actavis
    Actavis, Spain; Actavis, Hong Kong; Actavis, Netherlands; Actavis, Sweden; Actavis UK, United Kingdom
  • Topotecan ATB
    Antibiotice, Romania
  • Topotecan CF
    Centrafarm, Netherlands
  • Topotecan Cipla
    MC Pharma, Bulgaria
  • Topotecan Eagle
    Eagle Laboratories, Netherlands
  • Topotecan Ebewe
    Ebewe, Bulgaria; Ebewe, Estonia; Ebewe, Hungary; Ebewe, Romania
  • Topotecan Fresenius Kabi
    Fresenius Kabi, Denmark; Fresenius Kabi, Sweden; Fresenius Kabi Oncology, Netherlands
  • Topotecan Hikma
    Hikma, Netherlands
  • Topotecan Hospira
    Hospira, Austria; Hospira, Denmark; Hospira, Spain; Hospira, France; Hospira, Netherlands; Hospira, Norway; Hospira, Sweden; Hospira, United States; Hospira UK, United Kingdom
  • Topotecan Kabi
    Fresenius, Australia; Fresenius, Hungary; Fresenius Kabi, Bulgaria; Fresenius Kabi, Czech Republic; Fresenius Kabi, France; Fresenius Kabi, Romania; Fresenius Kabi Oncology, Austria; Fresenius Kabi Oncology, Estonia
  • Topotecan Labatec
    Labatec Pharma, Switzerland
  • Topotecan medac
    medac, Germany; medac, United Kingdom
  • Topotecan Medac
    medac, France
  • Topotecan Medison
    Intas, Israel
  • Topotecan Mylan
    Mylan, Belgium; Mylan, France; Mylan, Netherlands
  • Topotecan Oncoeurope
    Onco-Europe, Hungary
  • Topotecan Sandoz
    Sandoz, Canada; Sandoz, Netherlands
  • Topotecan Teva
    Teva, Belgium; Teva, Czech Republic; Teva, Spain; Teva, Lithuania; Teva, Latvia; Teva, Netherlands; Teva, Romania; Teva Pharmaceuticals, Poland; Teva Santé, France
  • Topotecan-Actavis
    Actavis Group, Russian Federation
  • Topotecane Accord
    Accord Healthcare, France
  • Topotecan-HAEMATO
    Haemato Pharm, Germany
  • Topotecano Accord
    Accord, Portugal
  • Topotecano Actavis
    Actavis, Portugal
  • Topotecano Eagle
    Eagle, Portugal
  • Topotecano Generis
    Generis, Portugal
  • Topotecano Hikma
    Hikma, Portugal
  • Topotecano Hospira
    Hospira, Portugal
  • Topotecano Kabi
    Fresenius Kabi, Portugal
  • Topotecano Mylan
    Mylan, Portugal
  • Topotecano Sandoz
    Sandoz, Portugal
  • Topotecano Stada
    Stada, Portugal
  • Topotecano Teva
    Teva Pharma, Portugal
  • Topotecano Venus Pharma
    Venus Pharma, Portugal
  • Topotel
    Fresenius, Philippines
  • Topovin
    Aurora, Greece
  • Xinze
    Ruinian Qianjin Pharmaceutical, China


BANBritish Approved Name
BANMBritish Approved Name (Modified)
ISInofficial Synonym
OSOfficial Synonym
Prop.INNProposed International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.