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Topotecan

In the US, Topotecan (topotecan systemic) is a member of the drug class miscellaneous antineoplastics and is used to treat Cancer, Cervical Cancer, Ovarian Cancer and Small Cell Lung Cancer.

US matches:

UK matches:

Scheme

Prop.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XX17

CAS registry number (Chemical Abstracts Service)

0123948-87-8

Chemical Formula

C23-H23-N3-O5

Molecular Weight

421

Therapeutic Categories

Cytostatic agent

Topoisomerase I inhibitor

Chemical Name

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimetylamino)metyl]-4-etyl-4,9-dihydroxy-

Foreign Names

  • Topotecanum (Latin)
  • Topotecan (German)
  • Topotecane (French)
  • Topotecan (Spanish)

Generic Names

  • Topotecan (OS: BAN)
  • Topotecan Hydrochloride (OS: BANM, USAN)
  • E 89/001 (IS)
  • NSC 609699 (IS)
  • SKF S-104864-A (SmithKlineBeec) (IS)

Brand Names

  • Cantop
    Dr. Reddy's, India
  • Firotex 4mg
    Actavis International, Vietnam
  • Hycamtin
    GlaxoSmithKline Manufacturing, Serbia; GSK, Pakistan; Novartis, Brazil; Novartis Europharm, Romania; Novartis, Slovenia; Smithkline Beecham, Cyprus
  • Oncotecan
    Zodiac, Brazil
  • Potactasol
    Actavis, Lithuania; Actavis Group, Poland; Actavis Group, Romania
  • Potekam
    Bio-Shar, Uruguay; DOSA, Paraguay
  • Topotacx
    Accord Farmaceutica, Brazil
  • Topotecam 4mg Varifarma
    Varifarma, Paraguay
  • Topotecan
    Accord Healthcare Ltd, Greece; Actavis Group, Greece; Fresenius Kabi Oncology, Malta; FU, Uruguay; Perulab, Peru; Sanderson, Peru; Teva Pharmaceuticals BV, Greece
  • Topotecan Accord
    Accord, Lithuania; Accord Healthcare, Cyprus; Evopharm, Slovakia
  • Topotecan Actavis
    Actavis, Lithuania; Actavis Group, Poland
  • Topotecan Alpha-Medical
    Alpha-Medical, Croatia (Hrvatska)
  • Topotecan Cipla
    Cipla, Poland
  • Topotecan Eagle
    Eagle Laboratories, Lithuania
  • Topotecan Ebewe
    Ebewe, Lithuania; Ebewe, Poland
  • Topotecan Farmaco Uruguayo
    Farmaco Urug., Paraguay
  • Topotecan Farmalider
    Farmalider, Spain
  • Topotecan Hexal
    Hexal, Germany
  • Topotecan Hospira
    Hospira, Cyprus; Hospira, Croatia (Hrvatska); Hospira, Lithuania; Hospira, Poland; Hospira UK, Serbia; Hospira UK Ltd, Greece
  • Topotecan Kabi
    Fresenius Kabi, Croatia (Hrvatska); Fresenius Kabi, Poland; Fresenius Kabi Oncology, Cyprus; Fresenius Kabi Oncology, Lithuania
  • Topotecan Logenex
    Logenex Pharm, Poland
  • Topotecan medac
    medac, Poland; medac, Slovakia
  • Topotecan Microsules
    Microsules Arg, Argentina
  • Topotecan Mylan
    Mylan, Poland
  • Topotecan Strides
    Strides Arcolab, Poland
  • Topotecan Teva
    Teva Pharma, Cyprus
  • Topotecan Teva 4mg/4ml
    Teva Pharma BV, Hungary
  • Topotecanum Accord
    Accord Healthcare, Poland
  • ACT Topotecan
    Actavis Pharma, Canada
  • Ai Tuo
    HengRui Medicine, China
  • Aoluona
    AosaiKang Pharmaceutical, China
  • Bo En
    Yangtze River Pharma, China
  • Camtoop
    Accord Farma, Mexico
  • Cloridrato de Topotecana Accord
    Accord Farmaceutica, Brazil
  • Hycamtin
    Bexal Farmaceutica, Spain; GlaxoSmithKline, Chile; GlaxoSmithKline, Georgia; GlaxoSmithKline, Hong Kong; GlaxoSmithKline, Croatia (Hrvatska); GlaxoSmithKline, Italy; GlaxoSmithKline, Kuwait; GlaxoSmithKline, Macedonia; GlaxoSmithKline, Malaysia; GlaxoSmithKline, Philippines; GlaxoSmithKline, Singapore; GlaxoSmithKline, Thailand; GlaxoSmithKline, Turkey; GlaxoSmithKline, Taiwan; GlaxoSmithKline, South Africa; GlaxoSmithKline Brasil, Brazil; Nippon Kayaku, Japan; Novartis, Belgium; Novartis, Czech Republic; Novartis, Denmark; Novartis, Estonia; Novartis, Ireland; Novartis, Lithuania; Novartis, Norway; Novartis, Slovakia; Novartis, Turkey; Novartis, United States; Novartis Europharm, Greece; Novartis Europharm Limited, Iceland; Novartis Pharma, Germany; Novartis Pharmaceuticals, Australia; Novartis Pharmaceuticals, Canada; Novartis Pharmaceuticals, Netherlands; Novartis Pharmaceuticals UK, United Kingdom; Sandoz, France; Sandoz, Sweden; SmithKline Beecham, Poland; GlaxoSmithKline China Investment, China; GlaxoSmithKline GSK, Oman
  • Hycamtin 0.25mg
    GlaxoSmithKline, Israel; Novartis, Luxembourg; Novartis Europharm, Austria; Novartis Pharma, Switzerland
  • Hycamtin 1 mg
    Novartis, Hungary
  • Hycamtin 1mg
    GlaxoSmithKline, Israel; Novartis, Luxembourg; Novartis Europharm, Austria; Novartis Pharma, Switzerland
  • Hycamtin 4mg
    Novartis Europharm, Austria; Novartis Pharma, Switzerland
  • Jin Xi Su
    Zhong Xing Han Fang Pharm, China
  • Lutecan
    Pharmazac SA, Greece
  • Oncotecan
    Medicamenta Ecuatoriana, Ecuador
  • Potactasol
    Actavis, France; Actavis, Latvia; Actavis, Netherlands; Actavis, Sweden; Actavis Baltics Eesti, Estonia; Actavis Group, Greece; Actavis UK, United Kingdom
  • Potactasol 1mg
    Actavis, Israel
  • Potactasol 4 mg
    Actavis, Hungary
  • Potactasol 4mg
    Actavis, Israel
  • Sheng Cheng
    Haibin Pharmaceutical, China
  • Tekan-L
    Mustafa Nevzat, Turkey
  • Topocan
    Ariti, Greece
  • Topokebir
    Aspen, Argentina
  • Topotecan
    Accord Healthcare, United Kingdom; medac, United Kingdom
  • Topotecan Accord
    Accord, Spain; Accord Healthcare, Czech Republic; Accord Healthcare, Germany; Accord Healthcare, Denmark; Accord Healthcare, Estonia; Accord Healthcare, Malta; Accord Healthcare, Netherlands; Accord Healthcare, Norway; Accord Healthcare, Romania; Accord Healthcare, Sweden
  • Topotecan Accord 1 mg/ml
    Accord Healthcare, Austria
  • Topotecan Accord Healthcare
    Accord Healthcare, Belgium; Accord Healthcare, Canada
  • Topotecan Actavis
    Actavis, Hong Kong; Actavis, Netherlands; Actavis, Sweden; Actavis Baltics Eesti, Estonia; Actavis UK, United Kingdom; Aurovitas, Spain; PUREN Pharma, Germany; S.C. Sindan-Pharma, Macedonia
  • Topotecan Eagle
    Eagle Laboratories, Spain
  • Topotecan Ebewe
    Ebewe, Estonia; Ebewe, Norway; Ebewe Pharma, Romania; Sandoz, Sweden
  • Topotecan Fair-Med
    Dianne Lee Regulatory Consultancy, Italy
  • Topotecan Heumann
    Heumann, Germany
  • Topotecan Hikma
    Hikma, Italy; Hikma Farmaceutica, Netherlands
  • Topotecan Hospira
    Hospira, Germany; Hospira, Estonia; Hospira, Spain; Hospira, France; Hospira Nordic, Denmark; Hospira UK, United Kingdom; Hospira UK, Macedonia; Pfizer, Netherlands; Pfizer, Sweden
  • Topotecan Hospira 4mg/4ml
    Hospira, Austria
  • Topotecan Hydrochloride
    Accord Healthcare, United States; Actavis, United States; Cipla, United States; Dr. Reddy's, United States; Fresenius Kabi, United States; Hospira, United States; Mylan, United States; Novast, United States; Sagent, United States; Teva, United States
  • Topotecan Kabi
    Fresenius Kabi Deutschland, Germany; Fresenius Kabi Oncology, Estonia
  • Topotecan Kabi 4 mg
    Fresenius Kabi, Hungary
  • Topotecan Logenex
    CareCept Medical GmbH, Germany
  • Topotecan medac 1mg/ml
    medac, Germany
  • Topotecan Mylan
    Mylan, France; Mylan, Netherlands
  • Topotecan Pfizer
    Pfizer, Canada
  • Topotecan Pharmagen
    PHARMAGEN, Czech Republic
  • Topotecan Sandoz
    Sandoz, Canada; Sandoz, Netherlands
  • Topotecan Strides
    Strides, Spain
  • Topotecan Teva
    Teva, Spain; Teva, Lithuania; Teva, Macedonia; Teva, Sweden; Teva Eesti, Estonia; Teva Nederland, Netherlands; TEVA Pharma, Romania; Teva Pharmaceuticals, Poland; Teva Santé, France
  • Topotecan Teva 1mg/ml
    Teva, Germany; Teva, Israel; Teva, Luxembourg
  • Topotecan Teva 4mg/4ml
    Teva, Germany
  • Topotecan-Actavis
    Actavis, Russian Federation
  • Topotecane Accord
    Accord Healthcare, France
  • Topotecan-HAEMATO 1mg
    HAEMATO PHARM, Germany
  • Topotecan-HAEMATO 4mg
    HAEMATO PHARM, Germany
  • Topotecan-Humanity
    Remedies, Georgia
  • Topotel
    Fresenius, Philippines
  • Topotu
    Onko-Koçsel, Turkey
  • Topovin
    Pharmanel, Greece
  • Topoxin
    Teva Ilac, Turkey
  • Toranex
    Fresenius, Mexico
  • Xinze
    Ruinian Qianjin Pharmaceutical, China

Glossary

TermDefinition
BANBritish Approved Name
BANMBritish Approved Name (Modified)
ISInofficial Synonym
OSOfficial Synonym
Prop.INNProposed International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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