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Simeprevir

In the US, Simeprevir (simeprevir systemic) is a member of the drug class protease inhibitors and is used to treat Hepatitis C.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

J05AE14

CAS registry number (Chemical Abstracts Service)

0923604-59-5

Chemical Formula

C38-H47-N5-O7-S2

Molecular Weight

749

Therapeutic Categories

Antiviral agent: Treatment of hepatitis C

Inhibitor of the NS3/A4 protease

Chemical Name

(2R,3aR,10Z,11aR,12aR,14aR)-N-(cyclopropanesulfonyl)-2-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-1 (WHO)

Foreign Names

  • Simeprevirum (Latin)
  • Simeprevir (German)
  • Siméprévir (French)
  • Simeprevir (Spanish)

Generic Names

  • Simeprevir (OS: USAN)
  • UNII-9WS5RD66HZ (IS)
  • Simeprevir Sodium (OS: JAN)
  • UNII-16U7H60184 (IS)

Brand Names

  • Galexos
    Janssen, Canada
  • Olysio
    Janssen, Iceland; Janssen, Slovakia; Janssen-Cilag, Germany; Janssen-Cilag, Poland; Janssen-Cilag International, Austria; Janssen-Cilag International NV, Slovenia; Johnson & Johnson, Croatia (Hrvatska); Janssen, Ireland; Janssen Pharma, United States; Janssen-Cilag, Belgium; Janssen-Cilag, Switzerland; Janssen-Cilag, France; Janssen-Cilag, United Kingdom; Medivir, Denmark; Medivir, Finland; Medivir, Sweden

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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