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Siltuximab

In the US, Siltuximab (siltuximab systemic) is a member of the drug class interleukin inhibitors and is used to treat Multicentric Castleman’s Disease.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L04AC11

CAS registry number (Chemical Abstracts Service)

0541502-14-1

Chemical Formula

C6450-H9932-N1688-O2016-S50

Molecular Weight

144981

Therapeutic Category

Antineoplastic agent

Chemical Name

immunoglobulin G1-kappa, anti-[Homo sapiensinterleukin 6 (IL6,IL-6)], chimeric monoclonal antibody;gamma1 heavy chain (1-449)[Mus musculusVH (IGHV5-9-4*01-(IGHD)-IGHJ4*01)[8.8.12](1-119)-Homo sapiensIGHG1*01 (120-449)], (222-213')-disulfide with kappa lig (WHO)

Foreign Names

  • Siltuximabum (Latin)
  • Siltuximab (German)
  • Siltuximab (French)
  • Siltuximab (Spanish)

Generic Names

  • Siltuximab (OS: USAN)
  • UNII-T4H8FMA7IM (IS)

Brand Names

  • Sylvant
    Janssen, Finland; Janssen, Ireland; Janssen, Sweden; Janssen Biotech, United States; Janssen-Cilag, Switzerland; Janssen-Cilag, Germany; Janssen-Cilag, Denmark; Janssen-Cilag, United Kingdom; Janssen-Cilag, Greece; Janssen-Cilag, Poland; Janssen-Cilag International, Austria; Janssen-Cilag International NV, Slovenia; Johnson & Johnson, Croatia (Hrvatska)

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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