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Ponatinib

In the US, Ponatinib (ponatinib systemic) is a member of the following drug classes: BCR-ABL tyrosine kinase inhibitors, multikinase inhibitors, VEGF/VEGFR inhibitors and is used to treat Acute Lymphoblastic Leukemia and Chronic Myelogenous Leukemia.

US matches:

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0943319-70-8

Chemical Formula

C29-H27-F3-N6-O

Molecular Weight

532

Therapeutic Category

Antineoplastic agent: Tyrosine kinase inhibitor

Chemical Name

3-[2-(imidazo[1,2-b]pyridazin-3-yl)etynyl]-4-metyl-N-{4-[(4-metylpiperazin-1-yl)metyl]-3-(trifluorometyl)phenyl}benzamide (WHO)

Foreign Names

  • Ponatinibum (Latin)
  • Ponatinib (German)
  • Ponatinib (French)
  • Ponatinib (Spanish)

Generic Names

  • Ponatinib (OS: USAN)
  • AP 24534 (IS)
  • UNII-4340891KFS (IS)
  • Ponatinib Hydrochloride (OS: USAN)
  • AP 24534 hydrochloride (IS)
  • UNII-96R6PU3D8J (IS)

Brand Names

  • Iclusig
    ARIAD, Denmark; Ariad Pharma, Slovenia; Haupt Pharma Amareg, Slovakia
  • Iclusing
    Ariad, Spain
  • Iclusig
    Ariad, Austria; Ariad, Ireland; Ariad, Norway; Ariad Pharma, Finland; Ariad Pharma, United Kingdom; Ariad Pharmaceuticals, France

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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