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In the US, Penicillamine (penicillamine systemic) is a member of the drug class antirheumatics and is used to treat Cystinuria, Rheumatoid Arthritis and Wilson's Disease.

US matches:

UK matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Disease-modifying antirheumatic drug, DMARD

Antidote: Treatment of heavy metal poisoning

Chelating agent

Treatment of Wilson's disease

Chemical Name

D-Valine, 3-mercapto-

Foreign Names

  • Penicillaminum (Latin)
  • Penicillamin (German)
  • Pénicillamine (French)
  • Penicilamina (Spanish)

Generic Names

  • Penicillamina (OS: DCIT)
  • Penicillamine (OS: JAN, USAN, BAN)
  • Pénicillamine (OS: DCF)
  • β-Mercaptovaline (IS)
  • Penicillamin (PH: Ph. Eur. 8)
  • Penicillamine (PH: BP 2016, Ph. Eur. 8, Ph. Int. 4, USP 38)
  • Pénicillamine (PH: Ph. Eur. 8)
  • Penicillaminum (PH: Ph. Eur. 8, Ph. Int. 4)

Brand Names

  • Artamin
    Biochemie, Lebanon; Sandoz, Austria; Sandoz, Malaysia; Sandoz, Oman
  • Artamine
    Biocheme, Egypt
  • Cilamin
    Panacea, India
  • Cuprenil
    CN Unifarm, Romania; Polfa Kutno, Latvia; Teva, Bulgaria; Teva, Lithuania; Teva Pharmaceuticals, Poland
  • Cuprimine
    Merck Sharp & Dohme, Brazil; Merck Sharp & Dohme, Taiwan; Spedrog-Caillon, Argentina; Valeant, United States; Valeant Pharmaceuticals International, Canada
  • Cupripen
    Rubio, Spain; Spedrog-Caillon, Argentina
  • Depen
    Meda, United States; Wallace, United States
  • Distamine
    Alliance Pharmaceuticals, United Kingdom
  • D-Penamine
    Alphapharm, Australia; Mylan, New Zealand
  • D-Penil
    AC Farma, Peru
  • Kelatine
    Medirex Pharma, Portugal
  • Metalcaptase
    Actavis, Slovakia; Harvester, Taiwan; Heyl, Czech Republic; Heyl, Germany; Heyl, Latvia; Sanolabor, Slovenia; Taisho Seiyaku, Japan
  • Penicillamine Ifet
    IFET, Greece
  • Penicillamine Kent
    Kent Pharmaceuticals, United Kingdom
  • Retadel
    Delta Pharma, Egypt
  • Trolovol
    Dexo, Portugal; Imaxio, France


BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.