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In the US, Macitentan (macitentan systemic) is a member of the drug class agents for pulmonary hypertension and is used to treat Pulmonary Hypertension.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of pulmonary hypertension

Endothelin receptor antagonist

Chemical Names

N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'-propylsulfamide (USAN)

N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'-propylsulfuric diamide (WHO)

Foreign Names

  • Macitentanum (Latin)
  • Macitentan (German)
  • Macitentan (French)
  • Macitent√°n (Spanish)

Generic Names

  • Macitentan (OS: USAN, JAN)
  • Macitentan (PH: JP XV)

Brand Names

  • Opsumit
    Actelion, Belgium; Actelion, Canada; Actelion, Switzerland; Actelion, Germany; Actelion, Finland; Actelion, Ireland; Actelion, Iceland; Actelion, Italy; Actelion, Netherlands; Actelion, Norway; Actelion, Poland; Actelion, Slovenia; Actelion, United States; Actelion Pharmaceuticals, Sweden; Actelion Pharmaceuticals UK, Austria; Actelion Pharmaceuticals UK, United Kingdom; Actelion, Denmark; Actelion, Israel


ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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