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Lumacaftor

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R07AX30

CAS registry number (Chemical Abstracts Service)

0936727-05-8

Chemical Formula

C24-H18-F2-N2-O5

Molecular Weight

452

Therapeutic Categories

Treatment of Cystic Fibrosis

CFTR (cystic fibrosis transmembrane regulator) channel activator

Chemical Name

3-{6-[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamido]-3-methylpyridin-2-yl}benzoic acid (WHO)

Foreign Names

  • Lumacaftorum (Latin)
  • Lumacaftor (German)
  • Lumacaftor (French)
  • Lumacaftor (Spanish)

Generic Names

  • Lumacaftor (OS: USAN)
  • EGP8L81APK (IS)
  • VX-809 (IS)

Brand Names

  • Orkambi (Lumacaftor and Ivacaftor)
    Vertex, United Kingdom; Vertex, United States; Vertex Pharmaceuticals, Germany

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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