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ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of Cystic Fibrosis

CFTR (cystic fibrosis transmembrane regulator) channel activator

Chemical Name

3-{6-[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamido]-3-methylpyridin-2-yl}benzoic acid (WHO)

Foreign Names

  • Lumacaftorum (Latin)
  • Lumacaftor (German)
  • Lumacaftor (French)
  • Lumacaftor (Spanish)

Generic Names

  • Lumacaftor (OS: USAN)
  • EGP8L81APK (IS)
  • VX-809 (IS)

Brand Names

  • Orkambi [+ Ivacaftor]
    Almac Pharma, Estonia; Vertex, Australia; Vertex, Switzerland; Vertex, Czech Republic; Vertex, Denmark; Vertex, France; Vertex, United Kingdom; Vertex, Ireland; Vertex, Lithuania; Vertex, Latvia; Vertex, Norway; Vertex, United States; Vertex Pharmaceuticals, Canada; Vertex Pharmaceuticals, Germany; Vertex Pharmaceuticals, Sweden; Vertex Pharmaceuticals, Slovenia; Vertex Pharmaceuticals Limited, Netherlands; Vertex Pharmaceutical Europe, Belgium
  • Orkambi 200mg/125mg [+ Ivacaftor]
    Vertex, Luxembourg
  • Orkambi 200mg/125mg [+ Ivacaftor] [pediatric]
    Vertex Pharmaceutical, Austria


ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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