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In the US, Lubiprostone (lubiprostone systemic) is a member of the drug class chloride channel activators and is used to treat Constipation, Constipation - Chronic, Constipation - Drug Induced, Irritable Bowel Syndrome and Opioid-Induced Constipation.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Prostaglandin analogue

Chemical Names

(-)-7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic acid (WHO)

7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptansäure (IUPAC)

Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)- (USAN)

Foreign Names

  • Lubiprostonum (Latin)
  • Lubiproston (German)
  • Lubiprostone (French)
  • Lubiprostona (Spanish)

Generic Names

  • Lubiprostone (OS: USAN, JAN, BAN)
  • RU-0211 (IS: RTechUeno)
  • SPI-0211 (IS: Sucampo)

Brand Names

  • Amitiza
    Sucampo, United States; Sucampo Pharma, Japan; Sucampo Pharma, Netherlands; Sucampo Pharma Europe, United Kingdom; Takeda Pharma, Switzerland
  • Modulex
    Procaps, Colombia


BANBritish Approved Name
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.