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Loperamide Oxide



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Antidiarrheal agent

Chemical Name

trans-4-(p-Chlorophenyl)-4-hydroxy-N,N-dimetyl-α,α-diphenyl-1-piperidinebutyramide 1-oxide

Foreign Names

  • Loperamidum oxidum (Latin)
  • Loperamid oxid (German)
  • Loperamide Oxyde (French)
  • Oxido de loperamida (Spanish)

Generic Names

  • Loperamide Oxide (OS: BAN)
  • R 58425 (Janssen) (IS)
  • Loperamide Oxide Monohydrate (PH: BP 2018)
  • Loperamide oxide monohydrate (PH: Ph. Eur. 9)
  • Loperamidi oxidum monohydricum (PH: Ph. Eur. 9)

Brand Names

  • Arestal
    Euro Registratie, Netherlands; Janssen-Cilag, Netherlands
  • Arestal 1 mg
    Janssen-Cilag, France


BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.