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In the US, Linaclotide (linaclotide systemic) is a member of the drug class guanylate cyclase-C agonists and is used to treat Constipation, Constipation - Chronic and Irritable Bowel Syndrome.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Chemical Name

[9-L-tyrosine]heat-stable enterotoxin (Escherischia coli)-(6-19)-peptide (WHO )

Foreign Names

  • Linaclotidum (Latin)
  • Linaclotid (German)
  • Linaclotide (French)
  • Linaclotida (Spanish)

Generic Names

  • Linaclotide (OS: USAN)

Brand Names

  • Axulta
    Ironwood Pharmaceuticals, Switzerland
  • Constella
    Actavis Specialty Pharmaceuticals, Canada; Allergan, Switzerland; Almirall, Austria; Almirall, Denmark; Almirall, Spain; Almirall, Finland; Almirall, United Kingdom; Almirall, Iceland; Almirall, Italy; Almirall, Norway; Almirall, Poland; Almirall, Sweden; Almirall Hermal, Germany
  • Linzess
    Forest, United States


ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.