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Levofolinic Acid

CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Antidote against folic acid antagonists

Detoxifying agent for antineoplastic treatment

Chemical Names

L-Glutamic acid, N-(4-((((6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)metyl)amino)benzoyl)-

L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)metyl)amino)benzoyl)-, (S)-

Foreign Names

  • Levofolinsäure (German)
  • Lévofolinique, acide (French)

Generic Names

  • (S)-Leucovorin (IS)
  • Levoleucovorin (IS)
  • L-Folinic acid (IS)
  • Calcium Levofolinate (OS: BAN)
  • Levofolinate Calcium (OS: JAN)
  • Levoleucovorin Calcium (OS: USAN)
  • CL 307782 (IS)
  • Elvorine (IS)
  • Isovorin (IS)
  • Levofolene (IS)
  • Levofolinic acid, calcium salt (IS)
  • LFA (IS)
  • UNII-778XL9VBS8 (IS)
  • Calcii levofolinas pentahydricus (PH: Ph. Eur. 8)
  • Calcium levofolinate pentahydrate (PH: Ph. Eur. 8)
  • Calcium Levofolinate Pentahydrate (PH: BP 2016)
  • Calciumlevofolinat-Pentahydrat (PH: Ph. Eur. 8)
  • Lévofolinate calcique pentahydraté (PH: Ph. Eur. 8)
  • Disodium levofolinate (IS)

Brand Names


BANBritish Approved Name
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
USANUnited States Adopted Name

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Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.