Ixabepilone
In the US, Ixabepilone (ixabepilone systemic) is a member of the drug class mitotic inhibitors and is used to treat Breast Cancer and Breast Cancer - Metastatic.
US matches:
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
L01DC04
CAS registry number (Chemical Abstracts Service)
0219989-84-1
Chemical Formula
C27-H42-N2-O5-S
Molecular Weight
506
Therapeutic Categories
Antineoplastic agent: Cytotoxic antibacterial
Epothilon B analogue
Chemical Names
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentametyl-3-[(E)-1-metyl-2-(2-metyltiazol-4-yl)etenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecan-5,9-dion (IUPAC)
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentametyl-3-[(1E)-1-(2-metyl-1,3-tiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione (WHO)
17-Oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12,16-pentametyl-3-[(1E)-1-metyl-2-(2-metyl-4-tiazolyl)etenyl]- (1S,3S,7S,10R,11S,12S,16R)- (USAN)
Foreign Names
- Ixabepilonum (Latin)
- Ixabepilon (German)
- Ixabépilone (French)
- Ixabepilona (Spanish)
Generic Names
- Ixabepilone (OS: USAN, JAN)
- Azaepothiolone B (IS)
- BMS 247550-01 (IS: Bristol-Myers)
- NSC-710428 (IS)
Brand Names
- Ixempra
Bristol Myers Squibb, Chile; Bristol-Myers Squibb, Switzerland; Bristol-Myers Squibb, Colombia; Bristol-Myers Squibb, Thailand; Bristol-Myers Squibb, Taiwan; Bristol-Myers Squibb, United States; Bristol-Myers Squibb, South Africa; Corden Pharma, Israel - Ixemprya
Bristol-Myers Squibb, Mexico
Glossary
| Term | Definition |
|---|---|
| IUPAC | International Union of Pure and Applied Chemistry |
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
| WHO | World Health Organization |
Further information on drug naming conventions: International Nonproprietary Names.
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