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Ivacaftor

In the US, Ivacaftor (ivacaftor systemic) is a member of the drug class CFTR potentiators and is used to treat Cystic Fibrosis.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R07AX02

CAS registry number (Chemical Abstracts Service)

0873054-44-5

Chemical Formula

C24-H28-N2-O3

Molecular Weight

392

Therapeutic Category

Treatment of Cystic Fibrosis

Chemical Names

N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (WHO)

3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimetyletyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo- (USAN)

Foreign Names

  • Ivacaftor (Latin)
  • Ivacaftor (German)
  • Ivacaftor (French)
  • Ivacaftor (Spanish)

Generic Names

  • Ivacaftor (OS: USAN, BAN)
  • UNII-1Y740ILL1Z (IS)
  • VX-770 (IS)

Brand Names

  • Kalydeco
    Vertex, Belgium; Vertex, Switzerland; Vertex, Denmark; Vertex, Spain; Vertex, France; Vertex, United Kingdom; Vertex, Ireland; Vertex, Lithuania; Vertex, Norway; Vertex, Poland; Vertex, United States; Vertex Pharmaceutical, Austria; Vertex Pharmaceuticals, Canada; Vertex Pharmaceuticals, Germany; Vertex Pharmaceuticals, Slovenia
  • Orkambi (Ivacaftor and Lumacaftor)
    Vertex, United Kingdom; Vertex, United States; Vertex Pharmaceuticals, Germany

International Drug Name Search

Glossary

TermDefinition
BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Important Notice: The Drugs.com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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