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Folinic Acid



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Antidote against folic acid antagonists

Chemical Names

5-formyl-5,6,7,8-tetrahydrofolic acid

5-formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid

5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutaminsäure (IUPAC)

5-Formyltetrahydropteroylglutamic acid

L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)metyl]amino]benzoyl]-, calcium salt (1:1)

N-[4'-[[(2-Amino-4-hydroxy-6-pteridyl)metyl]amino]benzoyl]-L-(+)-glutamic acid (WHO)

N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)metyl]-amino]benzoyl]-L-glutamic acid

N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)metyl]amino]benzoyl]glutamic acid

Foreign Names

Generic Names

  • Acide folinique (OS: DCF)
  • Folinic Acid (OS: BAN)
  • Leucovorin (OS: BAN)
  • Citrovorin (IS)
  • Citrovorum Factor (IS)
  • Citrovorum-Faktor (IS)
  • Folidan (IS)
  • Folinac (IS)
  • Folininsäure (IS)
  • Folinsäure SF (IS)
  • FTHF (IS)
  • Leuconostoc-citrovorum-factor (IS)
  • Disodium Folinate (OS: BANM)
  • Sodium folinate (IS)

Brand Names


BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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