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Evolocumab

In the US, Evolocumab (evolocumab systemic) is a member of the drug class PCSK9 inhibitors and is used to treat High Cholesterol, High Cholesterol - Familial Heterozygous and High Cholesterol - Familial Homozygous.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C10AX13

CAS registry number (Chemical Abstracts Service)

1256937-27-5

Chemical Formula

C6242-H9648-N1668-O1996-S56

Molecular Weight

141789

Therapeutic Categories

Lipid lowering agent for the treatment of homozygous familial hypercholesterolemia

Lipid modifying agent

Chemical Name

Immunoglobulin G2-lambda, anti-[Homo sapiensPCSK9 (proprotein convertase subtilisin/kexin type 9)], Homo sapiensmonoclonal antibody;gamma2 haevy chain (1-441)[Homo sapiensVH (IGHV1-18*01 (93.90%) -(IGHD)-IGHJ6*01))[8.8.8](1-115) -IGHG2*01 (CH1 (116-213), (WHO)

Foreign Names

  • Evolocumabum (Latin)
  • Evolocumab (German)
  • √Čvolocumab (French)
  • Evolocumab (Spanish)

Generic Names

Brand Names

  • Repatha
    Amgen, Germany; Amgen, United Kingdom; Amgen, United States; Amgen Switzerland, Switzerland

International Drug Name Search

Glossary

TermDefinition
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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