In the US, Evolocumab (evolocumab systemic) is a member of the drug class PCSK9 inhibitors and is used to treat Cardiovascular Risk Reduction, High Cholesterol, High Cholesterol - Familial Heterozygous and High Cholesterol - Familial Homozygous.
- Evolocumab Auto-Injectors and Prefilled Syringes
- Evolocumab On-Body Infusor
- Evolocumab Subcutaneous
ATC (Anatomical Therapeutic Chemical Classification)
CAS registry number (Chemical Abstracts Service)
Lipid lowering agent for the treatment of homozygous familial hypercholesterolemia
Lipid modifying agent
Immunoglobulin G2-lambda, anti-[Homo sapiensPCSK9 (proprotein convertase subtilisin/kexin type 9)], Homo sapiensmonoclonal antibody;gamma2 haevy chain (1-441)[Homo sapiensVH (IGHV1-18*01 (93.90%) -(IGHD)-IGHJ6*01))[8.8.8](1-115) -IGHG2*01 (CH1 (116-213), hinge (214-225), CH2 (226-334), CH3 (335-439), CHS (440-441))(116-441)], (129-214')-disulfide with lambda light chain (1'-215')[Homo sapiensV-LAMBDA (IGLV2-14*01 (95.90%) -IGLJ2*01)[9.3.9](1'-109') -IGLC2*01 (110'-2015')]; dimer (217-217''.218-218''.221-221''.224-224'')-tetrakisdisulfide (WHO)
- Evolocumabum (Latin)
- Evolocumab (German)
- Évolocumab (French)
- Evolocumab (Spanish)
- Evolocumab (OS: USAN)
- Evolocumab (Genetical Recombination) (OS: JAN)
- AMG-145 (IS)
- UNII-LKC0U3A8NJ (IS)
Amgen, Australia; Amgen, Bosnia & Herzegowina; Amgen, Belgium; Amgen, Canada; Amgen, Czech Republic; Amgen, Denmark; Amgen, Estonia; Amgen, Spain; Amgen, Finland; Amgen, United Kingdom; Amgen, Lithuania; Amgen, Latvia; Amgen, Norway; Amgen, Russian Federation; Amgen, Sweden; Amgen, Slovakia; Amgen, Turkey; Amgen, United States; Amgen Astellas BioPharma, Japan; Amgen Biotecnologia do Brasil, Brazil; Amgen Europe, Netherlands; Amgen Europe, Romania; Amgen Europe B.V., Israel; Amgen Europe BV, Greece; Amgen Europe BV, Iceland; Amgen Ltd., Ireland
- Repatha 140mg
Amgen, Germany; Amgen, Hungary; Amgen, Luxembourg; Amgen Europe, Austria
- Repatha 420mg
|JAN||Japanese Accepted Name|
|Rec.INN||Recommended International Nonproprietary Name (World Health Organization)|
|USAN||United States Adopted Name|
|WHO||World Health Organization|
Further information on drug naming conventions: International Nonproprietary Names.
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