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Erenumab

In the US, Erenumab (erenumab systemic) is a member of the drug class CGRP inhibitors and is used to treat Migraine Prevention.

US matches:

Scheme

Prop.INN

ATC (Anatomical Therapeutic Chemical Classification)

N02CX07

CAS registry number (Chemical Abstracts Service)

1582205-90-0

Chemical Formula

C6472-H9964-N1728-O2018-S50

Molecular Weight

145870

Therapeutic Categories

Antimigraine agent

Monoclonal antibody

Chemical Names

Heavy chainQVQLVESGGG VVQPGRSLRL SCAASGFTFS SFGMHWVRQA PGKGLEWVAV 50ISFDGSIKYS VDSVKGRFTI SRDNSKNTLF LQMNSLRAED TAVYYCARDR 100LNYYDSSGYY HYKYYGMAVW GQGTTVTVSS ASTKGPSVFP LAPCSRSTSE 150STAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS GLYSLSSVVT 200VPSSNFGTQT YTCNVDHKPS NTKVDKTVER KCCVECPPCP APPVAGPSVF 250LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVQFNWYVDG VEVHNAKTKP 300REEQFNSTFR VVSVLTVVHQ DWLNGKEYKC KVSNKGLPAP IEKTISKTKG 350QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY 400KTTPPMLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL 450SLSPGK 456Light chainQSVLTQPPSV SAAPGQKVTI SCSGSSSNIG NNYVSWYQQL PGTAPKLLIY 50DNNKRPSGIP DRFSGSKSGT STTLGITGLQ TGDEADYYCG TWDSRLSAVV 100FGGGTKLTVL GQPKANPTVT LFPPSSEELQ ANKATLVCLI SDFYPGAVTV 150AWKADGSPVK AGVETTKPSK QSNNKYAASS YLSLTPEQWK SHRSYSCQVT 200HEGSTVEKTV APTECS 216 (WHO )

Immunoglobulin G2-lambda, anti-[Homo sapiensCALCRL (calcitonin receptor like receptor, calcitonin gene-related peptide receptor, CGRPR, CGRP-R, CRLR)], Homo sapiensmonoclonal antibody (WHO)

Foreign Names

  • Erenumabum (Latin)
  • Erenumab (German)
  • Erénumab (French)
  • Erenumab (Spanish)

Generic Names

  • Erenumab (OS: USAN)
  • Erenumab-aooe (OS: FDA)
  • AMG 334 (USAN) (IS)
  • UNII-I5I8VB78VT (USAN) (IS)

Brand Names

  • Aimovig
    Amgen, United States; Novartis, Poland; Novartis Pharmaceuticals, Australia
  • Aimovig 70mg/ml
    Novartis Pharma, Switzerland

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Prop.INNProposed International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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