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CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Oral antidiabetic agent: Aldose reductase inhibitor

Chemical Name

5-[(Z,E)-β-Metylcinnamylidene]-4-oxo-2-tioxo-3-tiazolidineacetic acid

Foreign Names

  • Epalrestatum (Latin)
  • Epalrestat (German)
  • Epalrestat (French)
  • Epalrestat (Spanish)

Generic Names

  • Epalrestat (OS: JAN)
  • ONO 2235 (IS)
  • Epalrestat (PH: JP XVII)

Brand Names

  • Aldorin
    Eskayef, Bangladesh
  • Epalrestat
    Daiichi Sankyo Espha, Japan; Fuji Seiyaku, Japan; Kobayashi Kako, Japan; Kyowa Yakuhin, Japan; Medisa Shinyaku, Japan; Nichi-Iko Pharmaceutical, Japan; Nihon Generic, Japan; Nipro, Japan; Ohara Yakuhin, Japan; Pfizer Japan, Japan; Sawai Seiyaku, Japan; Takata Pharmaceutical, Japan; Tatsumi Kagaku, Japan; Tobishi Pharmaceutical, Japan; Towa Yakuhin, Japan; Yoshindo, Japan
  • Kinaldose
    Kotobuki Seiyaku, Japan
  • Kinedak
    Ono Yakuhin, Japan
  • Kineldar
    Kyorin Rimedio, Japan
  • Kinex
    Takeda Teva Pharma, Japan
  • Monedax
    Takeda Teva Pharma, Japan
  • Tang Lin
    Hainan Hailing Pharmacuetical, China; Yangtze River Pharma, China
  • YiHeng
    Shandong Dayin Yanghai Bio-Pharmaceutical Co., Ltd, China


ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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