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Eltrombopag

In the US, Eltrombopag (eltrombopag systemic) is a member of the drug class platelet-stimulating agents and is used to treat Aplastic Anemia, Idiopathic Thrombocytopenic Purpura, Thrombocytopenia and Thrombocytopenia Idiopathic.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

B02BX05

CAS registry number (Chemical Abstracts Service)

0496775-61-2

Chemical Formula

C25-H22-N4-O4

Molecular Weight

442

Therapeutic Categories

Hematopoietic growth factor: Stimulation of thrombopoiesis

Hemostatic agent: Treatment of thrombocytopenia

Thrombopoietin receptor agonist

Chemical Names

(Z)-3'-{N'-[1-(3,4-Dimetylphenyl)-3-metyl-5-oxo-1,5-dihydropyrazolyliden]hydrazin}-2'-hydroxybiphenyl-3-carbonsäure (IUPAC)

[1,1'-Biphenyl]-3-carboxylic acid, 3'-[(2Z)-[1-(3,4-dimetylphenyl)-1,5-dihydro-3-metyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-

3'-{(2Z)-2-[1-(3,4-dimetylphenyl)-3-metyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]diazanyl}-2'-hydroxybiphenyl-3-carboxylic acid (WHO)

Foreign Names

  • Eltrombopagum (Latin)
  • Eltrombopag (German)
  • Eltrombopag (French)
  • Eltrombopag (Spanish)

Generic Names

  • SB 497115 (IS)
  • UNII-S56D65XJ9G (IS)
  • Eltrombopag Olamine (OS: USAN, JAN)
  • SB-497115-GR (IS)
  • UNII-4U07F515LG (IS)

Brand Names

  • Eltrombopag
    Hetero, United States
  • Revolade
    Glaxo Smithkline, Lebanon; Glaxo Wellcome, Serbia; GlaxoSmithKline, Cyprus; GlaxoSmithKline, Poland; GSK, Peru; Novartis, Bosnia & Herzegowina; Novartis, Brazil; Novartis, Lithuania; Novartis, Turkey; Novartis Europharm, Slovenia; Novartis Europharm, Tunisia; Novartis Europharm Limited, Latvia
  • Revolade 50 mg
    Novartis, Hungary
  • Promacta
    Novartis, United States
  • Rebozet
    GlaxoSmithKline, Indonesia
  • Revolade
    Glaxo Operations UK, Macedonia; GlaxoSmithKline, Chile; GlaxoSmithKline, Croatia (Hrvatska); GlaxoSmithKline, Malaysia; GlaxoSmithKline, Philippines; GlaxoSmithKline, Singapore; GlaxoSmithKline, Thailand; GlaxoWellcome, Georgia; Novartis, Argentina; Novartis, Belgium; Novartis, Czech Republic; Novartis, Denmark; Novartis, Estonia; Novartis, Finland; Novartis, France; Novartis, Hong Kong; Novartis, Ireland; Novartis, Japan; Novartis, Norway; Novartis, New Zealand; Novartis, Portugal; Novartis, Sweden; Novartis, Slovakia; Novartis Europharm, Greece; Novartis Europharm, Romania; Novartis Europharm Limited, Iceland; Novartis Europharm Limited, Netherlands; Novartis Farmaceutica, Spain; Novartis Pharmaceuticals, Australia; Novartis Pharmaceuticals, Canada; Novartis Pharmaceuticals UK, United Kingdom
  • Revolade 25 mg
    Novartis, Hungary
  • Revolade 25mg
    Glaxo Wellcome, Israel; Novartis, Luxembourg; Novartis Europharm, Austria; Novartis Pharma, Switzerland; Novartis Pharma, Germany; GlaxoSmithKline GSK, Oman
  • Revolade 50mg
    Glaxo Wellcome, Israel; Novartis, Luxembourg; Novartis Europharm, Austria; Novartis Pharma, Switzerland; Novartis Pharma, Germany; GlaxoSmithKline GSK, Oman
  • Revolade 75mg
    Novartis Europharm, Austria; Novartis Pharma, Germany

Glossary

TermDefinition
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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