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Deoxyribonuclease I

ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Therapeutic Categories

Mucolytic agent

Debriding agent

DNA hydrolyzing enzyme

Chemical Name

DNA-hydrolyzing enzyme (endopeptidase); physiologically produced by the mammalian pancreas. Single polypeptide chain with two disulfide bridges. Obtained either from bovine pancreas or by recombinant technology

Foreign Names

  • Deoxyribonuclease I (German)
  • Desoxyribonuclease I (French)
  • Desoxirribonucleasa I (Spanish)

Generic Names

  • ADNase I (IS)
  • Desoxyribonuclease I (IS)
  • DNase I (IS)
  • Pancreatic deoxyribonuclease (IS)
  • Pancreatic DNase (IS)
  • Pancreatic Dornase (IS)
  • Thymonuclease (IS)
  • Desoxyribonuclease, Rind (IS)
  • DNase I, bovine (IS)
  • Pancreatic deoxyribonuclease, bovine (IS)
  • Pancreatic DNase, bovine (IS)
  • Pancreatic Dornase, bovine (IS)
  • Thymonuclease, bovine (IS)
  • Dornase Alfa (OS: BAN, USAN, Rec.INN)
  • Dornase Alfa (Genetical Recombination) (OS: JAN)
  • Deoxyribonuclease, human, recombinant (IS)
  • Desoxyribonuclease, human, rekombinant (IS)
  • DNase I, recombinant human (IS)
  • rhDNase (IS)

Brand Names

  • Elase (Deoxyribonuclease I and Fibrinolysin)
    Pfizer, Malaysia
  • Fibrolan (Deoxyribonuclease I and Fibrinolysin)
    Pfizer, Slovakia; Pfizer Luxembourg, Bosnia & Herzegowina; Pfizer, Switzerland; Pfizer, Poland
  • Pulmozyme
    Chugai Pharmaceutical, Japan; EU-Pharma, Netherlands; F. Hoffmann-La Roche LTD, Serbia; Fisher Farma, Netherlands; Genentech, United States; Haemato Pharm, Austria; Hoffmann-La Roche, Bosnia & Herzegowina; Hoffmann-La Roche Ltd, Latvia; Roche, Argentina; Roche, Australia; Roche, Belgium; Roche, Bulgaria; Roche, Brazil; Roche, Canada; Roche, Colombia; Roche, Czech Republic; Roche, Germany; Roche, Denmark; Roche, Ecuador; Roche, Estonia; Roche, Spain; Roche, Finland; Roche, France; Roche, Greece; Roche, Croatia (Hrvatska); Roche, Hungary; Roche, Ireland; Roche, Israel; Roche, Italy; Roche, Lithuania; Roche, Malta; Roche, Mexico; Roche, Netherlands; Roche, Norway; Roche, New Zealand; Roche, Oman; Roche, Poland; Roche, Portugal; Roche, Romania; Roche, Sweden; Roche, Turkey; Roche, Uruguay; Roche, South Africa; Roche Austria, Austria; Roche Products, United Kingdom; Roche, Iceland
  • Viscozyme
    Productos Roche, Chile


BANBritish Approved Name
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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