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In the US, Cevimeline (cevimeline systemic) is a member of the drug class cholinergic agonists and is used to treat Sjogren's Syndrome.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Muscarinic receptor agonist (parasympathomimetic agent, direct acting)

Chemical Names

(+/-)-cis-2-Metylspiro[1,3-oxatiolane-5,3'-quinuclidine] (WHO)

cis-2-Metylspiro(1,3-oxatiolane-5,3')quinuclidine hydrochloride hydrate (2:2:1)

Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)oxatiolane), 2'-metyl-, hydrochloride, hydrate (2:1), cis-

Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxatiolane], 2'-metyl-, cis- (USAN)

Foreign Names

  • Cevimelinum (Latin)
  • Cevimelin (German)
  • Céviméline (French)
  • Cevimelina (Spanish)

Generic Names

Brand Names

  • Evoxac
    Daiichi Sankyo, Taiwan; Daiichi Sankyo, Japan; Daiichi Sankyo, United States
  • Saligren
    Nippon Kayaku, Japan


ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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