Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Cosopt (dorzolamide / timolol ophthalmic)
- Omnipen (ampicillin)
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food/lifestyle interactions
ampicillin food/lifestyle
Applies to: Omnipen (ampicillin)
ADJUST DOSING INTERVAL: Certain penicillins may exhibit reduced gastrointestinal absorption in the presence of food. The therapeutic effect of the antimicrobial may be reduced.
MANAGEMENT: The interacting penicillin should be administered one hour before or two hours after meals. Penicillin V and amoxicillin are not affected by food and may be given without regard to meals.
References (6)
- Neu HC (1974) "Antimicrobial activity and human pharmacology of amoxicillin." J Infect Dis, 129, s123-31
- Welling PG, Huang H, Koch PA, Madsen PO (1977) "Bioavailability of ampicillin and amoxicillin in fasted and nonfasted subjects." J Pharm Sci, 66, p. 549-52
- McCarthy CG, Finland M (1960) "Absorption and excretion of four penicillins." N Engl J Med, 263, p. 315-26
- Cronk GA, Wheatley WB, Fellers GF, Albright H (1960) "The relationship of food intake to the absorption of potassium alpha-phenoxyethyl penicillin and potassium phenoxymethyl penicillin from the gastrointestinal tract." Am J Med Sci, 240, p. 219-25
- Klein JO, Sabath LD, Finland M (1963) "Laboratory studies on oxacillin. I: in vitro activity against staphylococci and some other bacterial pathogens. II: absorption and urinary excretion in normal young." Am J Med Sci, 245, p. 399-411
- Neuvonen PJ, Elonen E, Pentikainen PJ (1977) "Comparative effect of food on absorption of ampicillin and pivampicillin." J Int Med Res, 5, p. 71-6
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Travoprost ophthalmic
Travoprost ophthalmic is used for glaucoma, open angle, intraocular hypertension
Bimatoprost ophthalmic
Bimatoprost ophthalmic is used for glaucoma, open angle, intraocular hypertension
Dorzolamide ophthalmic
Dorzolamide ophthalmic is used for glaucoma, open angle, intraocular hypertension
Pilocarpine ophthalmic
Pilocarpine ophthalmic is used for glaucoma, glaucoma, narrow angle, glaucoma, open angle ...
Brimonidine ophthalmic
Brimonidine ophthalmic is used for eye redness, glaucoma, open angle, intraocular hypertension
Timolol ophthalmic
Timolol ophthalmic is used for glaucoma, open angle, intraocular hypertension
Learn more
Further information
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