Drug Interaction Report

Momelotinib can occasionally cause dangerous blood clots and using it together with conjugated estrogens topical may increase the risk. Also, the risk is increased with age, cigarette smoking, high blood pressure, or high cholesterol. Blood clots can lead to complications such as heart attack, pulmonary embolism (blockage of an artery in the lung), and stroke. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks but has determined that this is the best course of treatment for you has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience potential signs and symptoms of blood clots such as chest pain; shortness of breath; difficulty breathing; coughing up blood; sudden loss of vision; pain, redness, or swelling in an arm or leg; and numbness or weakness on one side of the body. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.