Drug Interaction Report
5 potential interactions and/or warnings found for the following 2 drugs:
- cisapride
- Extendryl PEM (methscopolamine / phenylephrine)
Interactions between your drugs
phenylephrine methscopolamine
Applies to: Extendryl PEM (methscopolamine / phenylephrine), Extendryl PEM (methscopolamine / phenylephrine)
Methscopolamine may increase the effects of phenylephrine on your blood pressure and heart rate. Before receiving these medications, you should let your doctor know if you have high blood pressure or heart disease. You may not be able to use one or both of these medications, or you may need closer monitoring by your doctor in order to use these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
methscopolamine cisapride
Applies to: Extendryl PEM (methscopolamine / phenylephrine), cisapride
Cisapride in no longer on the market in the US. Do not take cisapride with any other medication.
Drug and food/lifestyle interactions
cisapride food/lifestyle
Applies to: cisapride
Cisapride is no longer on the market in the US. Do not take cisapride with any other medication, food, or beverage.
**Cisapride (Propulsid) is no longer marketed in the United States. You should only be taking cisapride if you are obtaining the medication from your doctor though a Limited Access Program developed jointly by the manufacturer and the FDA.**
methscopolamine food/lifestyle
Applies to: Extendryl PEM (methscopolamine / phenylephrine)
Ask your doctor before using methscopolamine together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking methscopolamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phenylephrine food/lifestyle
Applies to: Extendryl PEM (methscopolamine / phenylephrine)
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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