Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- bifidobacterium longum
- pyrimethamine / sulfadoxine
Interactions between your drugs
pyrimethamine sulfadoxine
Applies to: pyrimethamine / sulfadoxine, pyrimethamine / sulfadoxine
Using pyrimethamine together with sulfadoxine can increase your risk of anemias. Contact your doctor if you experience any changes in your blood test or if you feel weak or fatigued. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sulfadoxine bifidobacterium longum
Applies to: pyrimethamine / sulfadoxine, bifidobacterium longum
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Coadministration of oral probiotic preparations with oral antibiotics may reduce the efficacy of the probiotic. It has been theorized that concomitant antibiotics may kill the live organisms found in lactobacillus-, bacillus coagulans-, and bifidobacteria-containing oral probiotic preparations. However, the clinical significance of the interaction has not been established.
MANAGEMENT: Although data are limited, it may be prudent to advise patients to take oral probiotics at least 1 to 2 hours before or after an oral antibiotic.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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