Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- faricimab ophthalmic
- vandetanib
Interactions between your drugs
vandetanib faricimab ophthalmic
Applies to: vandetanib, faricimab ophthalmic
GENERALLY AVOID: Coadministration of ophthalmic faricimab with other anti-vascular endothelial growth factor (VEGF) and/or other therapies (e.g., photodynamic therapy) for the treatment of neovascular (wet) age-related macular degeneration (nAMD), visual impairment due to diabetic macular edema (DMO), and/or visual impairment due to macular edema secondary to retinal vein occlusion (RVO) in the same eye has not been evaluated.
MANAGEMENT: According to some authorities, concomitant use of ophthalmic faricimab with other anti-VEGF products, systemic or ocular, and/or other therapies (e.g., photodynamic therapies) in the same eye should generally be avoided. Clinical data characterizing the extent of this interaction are not available. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.
References (3)
- (2024) "Product Information. Vabysmo (faricimab ophthalmic)." Roche Products Ltd
- (2024) "Product Information. Vabysmo (faricimab ophthalmic)." Genentech
- (2024) "Product Information. Vabysmo (faricimab ophthalmic)." Roche Products Pty Ltd
Drug and food/lifestyle interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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