Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- ponesimod
- Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid)
Interactions between your drugs
tetanus toxoid ponesimod
Applies to: Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid), ponesimod
ADJUST DOSING INTERVAL: The administration of inactivated, killed, or otherwise noninfectious vaccines during ponesimod therapy is generally safe but may be associated with a diminished or suboptimal immunologic response. Vaccination may be less effective during and for up to one to two weeks after discontinuation of ponesimod therapy.
MANAGEMENT: Immune response to vaccines may be reduced during and for up to one to two weeks after discontinuation of ponesimod therapy. Treatment with ponesimod should be paused 1 week prior to and for 4 weeks after a planned vaccination to allow the full effect of vaccination to occur.
References (1)
- (2021) "Product Information. Ponvory (ponesimod)." Janssen Pharmaceuticals
diphtheria toxoid ponesimod
Applies to: Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid), ponesimod
ADJUST DOSING INTERVAL: The administration of inactivated, killed, or otherwise noninfectious vaccines during ponesimod therapy is generally safe but may be associated with a diminished or suboptimal immunologic response. Vaccination may be less effective during and for up to one to two weeks after discontinuation of ponesimod therapy.
MANAGEMENT: Immune response to vaccines may be reduced during and for up to one to two weeks after discontinuation of ponesimod therapy. Treatment with ponesimod should be paused 1 week prior to and for 4 weeks after a planned vaccination to allow the full effect of vaccination to occur.
References (1)
- (2021) "Product Information. Ponvory (ponesimod)." Janssen Pharmaceuticals
pertussis, whole cell ponesimod
Applies to: Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid), ponesimod
ADJUST DOSING INTERVAL: The administration of inactivated, killed, or otherwise noninfectious vaccines during ponesimod therapy is generally safe but may be associated with a diminished or suboptimal immunologic response. Vaccination may be less effective during and for up to one to two weeks after discontinuation of ponesimod therapy.
MANAGEMENT: Immune response to vaccines may be reduced during and for up to one to two weeks after discontinuation of ponesimod therapy. Treatment with ponesimod should be paused 1 week prior to and for 4 weeks after a planned vaccination to allow the full effect of vaccination to occur.
References (1)
- (2021) "Product Information. Ponvory (ponesimod)." Janssen Pharmaceuticals
haemophilus b conjugate (HbOC) vaccine ponesimod
Applies to: Tetramune (diphtheria toxoid / haemophilus b conjugate (hboc) vaccine / pertussis, whole cell / tetanus toxoid), ponesimod
ADJUST DOSING INTERVAL: The administration of inactivated, killed, or otherwise noninfectious vaccines during ponesimod therapy is generally safe but may be associated with a diminished or suboptimal immunologic response. Vaccination may be less effective during and for up to one to two weeks after discontinuation of ponesimod therapy.
MANAGEMENT: Immune response to vaccines may be reduced during and for up to one to two weeks after discontinuation of ponesimod therapy. Treatment with ponesimod should be paused 1 week prior to and for 4 weeks after a planned vaccination to allow the full effect of vaccination to occur.
References (1)
- (2021) "Product Information. Ponvory (ponesimod)." Janssen Pharmaceuticals
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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