Drug Interaction Report

Talk to your doctor before using bosentan together with ritonavir. Combining these medications may significantly increase the blood levels of bosentan, potentially increasing the risk of side effects. You may need a dose adjustment if you have been receiving bosentan and are starting treatment with ritonavir, or vice versa. In addition, you may need more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Talk to your doctor before using bosentan together with lopinavir. Combining these medications may increase the blood levels of bosentan to dangerous levels, increasing the risk of side effects. You may need a dose adjustment if you have been receiving bosentan and are starting treatment with lopinavir, or vice versa. In addition, you may need more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ritonavir should be taken with food to lessen gastrointestinal side effects. It is important that you take this medication exactly as prescribed by your doctor. Do not change your treatment or stop treatment without first talking to your doctor.

Food may affect the absorption of lopinavir-ritonavir (brand name Kaletra) depending on whether you are taking the oral solution or the tablet. The oral solution should be taken with food to enhance absorption and help it work better. The tablet formulation can be take with or without food. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.