Drug Interaction Report
This report displays the potential drug interactions for the following 2 drugs:
- Cardene SR (nicardipine)
Interactions between your drugs
Applies to: Cardene SR (nicardipine), tocilizumab
Tocilizumab may decrease the blood levels and effects of niCARdipine. You may need a dose adjustment if you have been receiving niCARdipine and are starting treatment with tocilizumab. Likewise, if you have been receiving both medications, the dose of niCARdipine may need to be adjusted when tocilizumab is discontinued. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Cardene SR (nicardipine)
You should avoid or limit the consumption of grapefruit and grapefruit juice if you are receiving treatment with niCARdipine. Grapefruit juice can significantly increase the blood levels and effects of medications like niCARdipine. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.