Excipient (pharmacologically inactive substance)
Medically reviewed by Drugs.com. Last updated on Nov 23, 2020.
What is it?
Hypromellose, also commonly known as hydroxypropyl methycellulose (HPMC) is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry. It has also been used as a rate-controlling polymer for sustained-release dose forms.
As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes. In the US, it is available over-the-counter (OTC) in such products as Isopto Tears and Nature’s Tears.
Top Medications with this excipient
- Acetaminophen, Diphenhydramine Hydochloride and Phenylephrine Hydrochloride 650 mg / 25 mg / 10 mg
- Allegra-D 24 Hour 180 mg / 240 mg
- Alprazolam Extended Release 0.5 mg
- Alprazolam Extended Release 3 mg
- Aspirin Enteric Coated 81 mg
- Cetirizine Hydrochloride 5 mg
- Cetirizine Hydrochloride 10 mg
- Enjuvia synthetic B, 0.45 mg
- Excedrin Migraine (Tablet) acetaminophen 250 mg / aspirin 250 mg / caffeine 65 mg
- Excedrin Tension Headache acetaminophen 500 mg / caffeine 65 mg
- Gemfibrozil 600 mg
- Hydrochlorothiazide and Losartan Potassium 25 mg / 100 mg
- Morphine Sulfate Extended-Release 15 mg
- Oforta fludarabine phosphate 10 mg
- Omeprazole Delayed Release 40 mg
- Ropinirole Hydrochloride 5 mg
- Salsalate 500 mg
- Simvastatin 40 mg
- Striant 30 mg
- Tylenol Arthritis Pain 650 mg
 Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
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