Hypromellose 2208 (4000 MPa.s)
Excipient (pharmacologically inactive substance)
What is it?
Hypromellose, also commonly known as hydroxypropyl methycellulose (HPMC) is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry.[1] It has also been used as a rate-controlling polymer for sustained-release dose forms.
As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes.[2] In the US, it is available over-the-counter (OTC) in such products as Isopto Tears and Nature’s Tears.
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Innovate Us. What is Hypromellose? http://www.innovateus.net/health/what-hypromellose. Accessed 08/19/2011
Top Medications with this excipient
- Alfuzosin Hydrochloride Extended Release 10 mg (Apotex Corp.)
- Alprazolam Extended Release 0.5 mg (Aurobindo Pharma Limited )
- Alprazolam Extended Release 3 mg (Aurobindo Pharma Limited)
- Alprazolam Extended Release 1 mg (Aurobindo Pharma Limited)
- Alprazolam Extended Release 2 mg (Aurobindo Pharma Limited)
- Carbidopa and Levodopa Extended Release 25 mg / 100 mg (Caraco Pharmaceutical Laboratories)
- Carbidopa and Levodopa Extended Release 50 mg / 200 mg (Caraco Pharmaceutical Laboratories)
- Carbidopa and Levodopa Extended-Release 25 mg / 100 mg (Accord Healthcare, Inc.)
- Carbidopa and Levodopa Extended-Release 50 mg / 200 mg (Accord Healthcare, Inc.)
- Donnatal Extentabs 0.0582 mg / 0.3111 mg / 48.6 mg / 0.0195 mg (PBM Pharmaceuticals)
- Minocycline Hydrochloride Extended-Release 135 mg (Aurobindo Pharma Limited)
- Minocycline Hydrochloride Extended-Release 90 mg (Aurobindo Pharma Limited)
- Minocycline Hydrochloride Extended-Release 45 mg (Aurobindo Pharma Limited)
- Venlafaxine Hydrochloride Extended Release 150 mg (Sun Pharmaceutical Industries Ltd)
- Venlafaxine Hydrochloride Extended Release 37.5 mg (Sun Pharmaceuticals)
- Venlafaxine Hydrochloride Extended Release 75 mg (Sun Pharmaceuticals)
- Zgesic acetaminophen 600 mg / phenyltoloxamine citrate 66 mg (Capellon Pharmaceuticals)
