Ethylcelluloses
Excipient (pharmacologically inactive substance)
What is it?
Ethylcellulose is a free-flowing, white to light tan powder used in the pharmaceutical and food manufacturing industries. It is prepared from wood pulp or cotton by treatment with alkali and ethylation of the alkali cellulose with ethyl chloride. Ethylcellulose is used in pharmaceutical industry as a coating agent, flavoring fixative, tablet binder and filler, and as a viscosity-increasing agent. Ethyl cellulose is also used in the food industry as an emulsifier.[1][2]
There is very limited data detailing possible side effects of ethylcellulose; however it is included in the FDA generally regarded as safe (GRAS) Database of Substances (SCOGS) Reviews.[3]
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Food and Agriculture Organization of the United States. Prepared at the 26th JECFA (1982), published in FNP 25 ( 1982) and FNP. 52 (1992). Accessed March 31, 2012. Ethylcellulose. http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-178.pdf
[3] FDA’s SCOGS database; Ethylcellulose; SCOGS-Report Number: 25; http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=365 Accessed March 31, http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=119
Top Medications with this excipient
- Amoxicillin and Clavulanate Potassium 875 mg / 125 mg (Lek Pharmaceuticals)
- Amoxicillin and Clavulanate Potassium 875 mg / 125 mg (Sandoz Pharmaceuticals Inc.)
- Amoxicillin and Clavulanate Potassium 875 mg / 125 mg (Aurobindo Pharma Limited)
- Amoxicillin and Clavulanate Potassium 500 mg / 125 mg (Sandoz Pharmaceuticals Inc.)
- Budeprion XL 150 mg (Teva Pharmaceuticals USA)
- Bupropion Hydrochloride Extended-Release (XL) 300 mg (Anchen Pharmaceuticals, Inc.)
- Bupropion Hydrochloride Extended-Release (XL) 150 mg (Anchen Pharmaceuticals, Inc.)
- Embeda morphine 20 mg / naltrexone 0.8 mg (Pfizer Inc)
- Methylphenidate Hydrochloride Extended-Release 36 mg (Mallinckrodt, Inc.)
- Methylphenidate Hydrochloride Extended-Release 54 mg (Mallinckrodt, Inc.)
- Methylphenidate Hydrochloride Extended-Release 27 mg (Mallinckrodt, Inc.)
- Omeprazole 20 mg (Mylan Pharmaceuticals Inc.)
- Orphenadrine Citrate Extended Release 100 mg (Sandoz Pharmaceuticals Inc.)
- Propranolol Hydrochloride Extended Release 160 mg (Actavis)
- Quetiapine Fumarate 100 mg (Apotex Corp.)
- Ropinirole Hydrochloride Extended-Release 6 mg (Dr. Reddys Laboratories Limited)
- Ropinirole Hydrochloride Extended-Release 6 mg (Sandoz Inc.)
- Venlafaxine Hydrochloride Extended Release 37.5 mg (Torrent Pharma Inc)
- Venlafaxine Hydrochloride Extended Release 37.5 mg (Wockhardt USA LLC.)
- Venlafaxine Hydrochloride Extended Release 37.5 mg (Dr.Reddy's Laboratories Ltd.)
