Edetate Calcium Disodium
Medically reviewed by Drugs.com. Last updated on Jan 30, 2024.
Excipient (pharmacologically inactive substance)
What is it?
Edetate calcium disodium ([CH2N(CH2CO2H)2]2, also known as calcium EDTA) is a chelating agent, and is capable of removing a heavy metal, such as lead or mercury, from the blood circulatory system. Edetate calcium disodium is used to treat lead poisoning. These agents also function as chelating agents in cosmetic formulations. Clinical tests reported no absorption of an EDTA salt through the skin, and the Cosmetic Ingredient Review Expert Panel found that these ingredients are safe as used in cosmetic formulations. In industry, EDTA is mainly used to sequester metal ions in aqueous solution, and to improve stability.[1][2]
List of medications using Edetate Calcium Disodium
- Acetaminophen and Hydrocodone Bitartrate 500 mg / 5 mg
- Chlordiazepoxide Hydrochloride 10 mg
- Diphenhydramine Hydrochloride 25 mg
- Fluoxetine Hydrochloride 20 mg
- Hydroxyurea 500 mg
- Lescol 20 mg
- Lescol 40 mg
- Loxapine Succinate 5 mg
- Loxapine Succinate 50 mg
- Loxapine Succinate 25 mg
- Oxazepam 10 mg
- Phenytoin Sodium Extended 100 mg
- Phenytoin Sodium Extended 100 mg
- Phrenilin with Caffeine and Codeine acetaminophen 325 mg / butalbital 50 mg / caffeine 40 mg / codeine phosphate 30 mg
- Surmontil 50 mg
- Temazepam 30 mg
- Temazepam 15 mg
- Tetracycline Hydrochloride 250 mg
- Tetracycline Hydrochloride 500 mg
- Tylenol Extra Strength 500 mg
References
- [1]Lanigan RS, Yamarik TA. Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA. Int J Toxicol. 2002;21 Suppl 2:95-142. http://www.ncbi.nlm.nih.gov/pubmed/12396676
- [2]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.