Copegus and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Copegus (ribavirin).
ribavirin food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.
MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.
References
- "Product Information. Copegus (ribavirin)." Roche Laboratories (2003):
- "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation (2004):
Copegus drug interactions
There are 18 drug interactions with Copegus (ribavirin).
Copegus disease interactions
There are 4 disease interactions with Copegus (ribavirin) which include:
More about Copegus (ribavirin)
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- During pregnancy
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- Drug class: inhaled anti-infectives
- Breastfeeding
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.