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Copegus and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Copegus (ribavirin).

Moderate

ribavirin food

Moderate Food Interaction

ADJUST DOSING INTERVAL: Food enhances the oral absorption and bioavailability of ribavirin. Administration of a single oral dose of ribavirin following a high-fat meal delayed absorption (Tmax was doubled) but increased the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) by up to 70% compared to administration in the fasting state.

MANAGEMENT: To ensure maximal oral absorption, ribavirin should be administered with or immediately after a meal.

References

  1. "Product Information. Copegus (ribavirin)." Roche Laboratories (2003):
  2. "Product Information. Rebetol (ribavirin)." Schering-Plough Corporation (2004):

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Copegus drug interactions

There are 18 drug interactions with Copegus (ribavirin).

Copegus disease interactions

There are 4 disease interactions with Copegus (ribavirin) which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.