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Ru-Hist D (old formulation) (phenylephrine / pyrilamine) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with Ru-Hist D (old formulation) (phenylephrine / pyrilamine):

Moderate

pyrilamine ↔ food

Moderate Food Interaction

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.

MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References

  1. Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
  2. Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
  3. "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc, Rockville, MD.
  4. "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
View all 4 references

Ru-Hist D (old formulation) (phenylephrine / pyrilamine) drug interactions

There are 1004 drug interactions with Ru-Hist D (old formulation) (phenylephrine / pyrilamine)

Ru-Hist D (old formulation) (phenylephrine / pyrilamine) disease interactions

There are 11 disease interactions with Ru-Hist D (old formulation) (phenylephrine / pyrilamine) which include:

More about Ru-Hist D (old formulation) (phenylephrine / pyrilamine)

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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