Macimorelin and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with macimorelin.
Macimorelin Food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food reduces the oral bioavailability of macimorelin. According to the product labeling, administration with a liquid meal decreased macimorelin peak plasma concentration (Cmax) and systemic exposure (AUC) by 55% and 49%, respectively, compared to administration under fasting conditions (i.e., for at least 8 hours).
MANAGEMENT: Macimorelin should be administered after fasting for at least 8 hours.
References (1)
- (2018) "Product Information. Macrilen (macimorelin)." Aeterna Zentaris
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Macimorelin drug interactions
There are 348 drug interactions with macimorelin.
Macimorelin disease interactions
There is 1 disease interaction with macimorelin which include:
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- Drug class: growth hormones
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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