Didronel IV and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Didronel IV (etidronate).
etidronate multivitamins with minerals
Moderate Drug Interaction
ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.
MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 2 hours before or 2 hours after the bisphosphonate dose.
References
- "Product Information. Fosamax (alendronate)." Merck & Co., Inc PROD (2001):
- Darcy PF "Nutrient-drug interactions." Adverse Drug React Toxicol Rev 14 (1995): 233-54
- "Product Information. Skelid (tiludronate)." Sanofi Winthrop Pharmaceuticals PROD
- "Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals PROD (2001):
- "Product Information. Bonefos (clodronate)." Rhone-Poulenc Rorer Canada Inc (2001):
- "Product Information. Boniva (ibandronate)." Roche Laboratories (2005):
etidronate food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food, especially calcium-containing food such as dairy products, significantly decreases the bioavailability of oral etidronate.
MANAGEMENT: Oral etidronate should be administered on an empty stomach and no other food or drink should be taken within least 2 hours of administration.
References
- "Product Information. Didronel (etidronate)." Procter and Gamble Pharmaceuticals (2022):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Didronel IV drug interactions
There are 175 drug interactions with Didronel IV (etidronate).
Didronel IV disease interactions
There are 3 disease interactions with Didronel IV (etidronate) which include:
More about Didronel IV (etidronate)
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: bisphosphonates
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.